Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1F | O60840 | 10/20 | 0.61 |
| ▸ | CACNA1D | Q01668 | 10/20 | 0.61 |
| ▸ | CACNA1S | Q13698 | 10/20 | 0.61 |
| ▸ | CACNA1C | Q13936 | 10/20 | 0.61 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9513433 | 0.96 | CACNA1F (0.68) | CACNA1FCACNA1DCACNA1SCACNA1CACHE | |
| SCHEMBL9505389 | 0.96 | CACNA1F (0.68) | CACNA1FCACNA1DCACNA1SCACNA1CACHE | |
| SCHEMBL11819347 | 0.90 | CACNA1F (0.72) | CACNA1FCACNA1DCACNA1SCACNA1CACHE | |
| SCHEMBL9677428 | 0.89 | CACNA1F (0.61) | CACNA1FCACNA1DCACNA1SCACNA1CACHE | |
| SCHEMBL11774845 | 0.88 | CACNA1F (0.60) | CACNA1FCACNA1DCACNA1SCACNA1CACHE | |
| SCHEMBL10861491 | 0.86 | CACNA1F (0.67) | CACNA1FCACNA1DCACNA1SCACNA1CACHE | |
| SCHEMBL9503033 | 0.86 | CACNA1F (0.80) | CACNA1FCACNA1DCACNA1SCACNA1CACHE | |
| SCHEMBL7275780 | 0.86 | CACNA1F (0.67) | CACNA1FCACNA1DCACNA1SCACNA1CACHE | |
| SCHEMBL9513394 | 0.84 | ABCC1 (0.58) | CACNA1FCACNA1DCACNA1SCACNA1CADORA3 | |
| SCHEMBL9675896 | 0.84 | CACNA1F (0.60) | CACNA1FCACNA1DCACNA1SCACNA1CACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0212340-B1 | 2-(heteroalkyl)-1,4-dihydropyridines, process for their preparations and pharmaceutical compositions containing them | BOEHRINGER MANNHEIM ITALIA (IT) | 1993-10-27 | — | — | EP | claimed |
| EP-0212340-B1 | 2-(heteroalkyl)-1,4-dihydropyridines, process for their preparations and pharmaceutical compositions containing them | BOEHRINGER MANNHEIM ITALIA (IT) | 1993-10-27 | — | — | EP | disclosed |
| US-4839348-A | HYPOTENSIVE AGENTS; ANTICOAGULANTS, ANTIISCHEMIC AGENTS | BOEHRINGER BIOCHEMIA ROBIN S.P.A. (IT) | 1989-06-13 | — | — | US | disclosed |