Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9514286 | 1.00 | CYP4F2 (0.40) | CYP4F2CYP4A11HTTALDH1A1TRPA1 | |
| SCHEMBL11399991 | 0.86 | MAPT (0.45) | CYP4F2CYP4A11HTTPKMMEN1 | |
| SCHEMBL9514260 | 0.85 | CYP4F2 (0.57) | CYP4F2CYP4A11HTTPKMMEN1 | |
| SCHEMBL9511878 | 0.85 | CYP4F2 (0.57) | CYP4F2CYP4A11HTTPKMMEN1 | |
| SCHEMBL4293341 | 0.78 | CYP4F2 (0.39) | CYP4F2CYP4A11HTTALDH1A1PKM | |
| SCHEMBL9512961 | 0.78 | ALDH1A1 (0.40) | CYP4F2CYP4A11ALDH1A1TRPA1PTGS2 | |
| SCHEMBL469310 | 0.77 | CYP4F2 (0.40) | CYP4F2CYP4A11HTTALDH1A1PKM | |
| SCHEMBL10178677 | 0.74 | TP53 (0.36) | CYP4F2CYP4A11HTTPKMTHRB | |
| SCHEMBL1620624 | 0.74 | CYP4F2 (0.41) | CYP4F2CYP4A11HTTALDH1A1TRPA1 | |
| SCHEMBL2142612 | 0.74 | CYP4F2 (0.71) | CYP4F2CYP4A11HTTALDH1A1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0353448-B1 | Sulfon amides, process for their preparation and pharmaceutical preparations containing them | BOEHRINGER MANNHEIM GMBH (DE) | 1993-10-27 | — | — | EP | disclosed |
| US-4981873-A | ANTICOAGULANTS | BOEHRINGER MANNHEIM GMBH (DE) | 1991-01-01 | — | — | US | disclosed |
| EP-0353448-A1 | Sulfon amides, process for their preparation and pharmaceutical preparations containing them | Roche Diagnostics GmbH (DE) | 1990-02-07 | — | — | EP | disclosed |