SCHEMBL9511573

SCHEMBL9511573

CC(C)C(=O)Nc1cccc2c1C(=O)c1ccccc1C2=O

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.71
MAPT P10636 2/20 0.60
L3MBTL1 Q9Y468 2/20 0.60
EGFR P00533 1/20 0.60
PABPC1 P11940 1/20 0.60
MAPK1 P28482 1/20 0.60
RAB9A P51151 1/20 0.60
SMN1; SMN2 Q16637 1/20 0.60
TDP1 Q9NUW8 1/20 0.60
MDM4 O15151 2/20 0.56
TP53 P04637 2/20 0.56
MEN1 O00255 1/20 0.54
ALDH1A1 P00352 1/20 0.54
POLB P06746 1/20 0.54
GAA P10253 1/20 0.54
DNMT1 P26358 1/20 0.54
RAD52 P43351 1/20 0.54
SMARCA2 P51531 1/20 0.54
KMT2A Q03164 1/20 0.54
CETP P11597 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20892849 0.94 MAOA (0.62) MAOAMAPTL3MBTL1EGFRPABPC1
SCHEMBL5804633 0.88 MAOA (0.68) MAOAMAPTL3MBTL1EGFRPABPC1
SCHEMBL10136191 0.85 MAOA (0.64) MAOAMAPTL3MBTL1EGFRPABPC1
SCHEMBL6366669 0.84 MAOA (0.62) MAOAMAPTL3MBTL1EGFRPABPC1
SCHEMBL16772820 0.84 MAOA (0.62) MAOAMAPTL3MBTL1EGFRPABPC1
SCHEMBL2601918 0.83 MAOA (1.00) MAOAMAPTL3MBTL1EGFRPABPC1
SCHEMBL10530825 0.83 MAOA (0.66) MAOAMAPTL3MBTL1EGFRPABPC1
SCHEMBL11742788 0.82 MAOA (0.73) MAOAMAPTL3MBTL1EGFRPABPC1
SCHEMBL10204003 0.82 MAOA (0.59) MAOAMAPTL3MBTL1EGFRPABPC1
SCHEMBL1304154 0.81 MAOA (0.59) MAOAMAPTL3MBTL1EGFRPABPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100093747-A1 METHOD OF INDUCING NEGATIVE CHEMOTAXIS CELTAXSYS, INC. 2010-04-15 US disclosed
EP-0409636-B1 THERMAL TRANSFER IMAGING USING ALKYLCARBONYLAMINO-ANTHRAQUINONE DYES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-09-01 EP disclosed
US-4988664-A THERMAL TRANSFER IMAGE, LAYER WITH ANTHRAQUINONE DYE, MULTILAYER ELEMENT FOR TEXTILES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-01-29 US disclosed
EP-0409636-A1 Thermal transfer imaging using alkylcarbonylamino-anthraquinone dyes MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-01-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100093747-A1 METHOD OF INDUCING NEGATIVE CHEMOTAXIS PMAIP1, CDC42, DCX MAOA 4528/4885MAPT 4842/4885L3MBTL1 1285/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.