SCHEMBL951162

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12946440	0.97	KDR (0.46)	KDRAURKACHEK1BUB1NUAK1
	SCHEMBL948918	0.93	KDR (0.44)	KDRAURKACHEK1HRH3ROCK2
	SCHEMBL949783	0.92	KDR (0.48)	KDRAURKACHEK1HRH3ROCK2
	SCHEMBL948293	0.91	KDR (0.42)	KDRAURKACHEK1HRH3ROCK2
	SCHEMBL949784	0.90	KDR (0.48)	KDRAURKACHEK1BUB1NUAK1
	SCHEMBL949291	0.89	KDR (0.45)	KDRAURKACHEK1HRH3ROCK2
	SCHEMBL12946252	0.89	SMN1; SMN2 (0.39)	KDRROCK2BUB1PLA2G1BCYP1A2
	SCHEMBL951371	0.88	KDR (0.53)	KDRAURKACHEK1ROCK2ROCK1
	SCHEMBL12946427	0.88	KDR (0.46)	KDRAURKACHEK1BUB1NUAK1
	SCHEMBL948495	0.88	KDR (0.41)	KDRAURKACHEK1BUB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.