SCHEMBL9511637

SCHEMBL9511637

CCC(C)(C)c1ccc(OC([C]=O)C(C)=O)c(C(C)(C)CC)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 6/20 0.52
NPSR1 Q6W5P4 5/20 0.52
SMN1; SMN2 Q16637 5/20 0.52
MEN1 O00255 4/20 0.52
KMT2A Q03164 4/20 0.52
ALDH1A1 P00352 1/20 0.52
MAPT P10636 4/20 0.40
HTT P42858 3/20 0.40
UBE2N P61088 2/20 0.40
GLA P06280 1/20 0.40
MITF O75030 1/20 0.40
RAB9A P51151 3/20 0.37
RAD52 P43351 2/20 0.37
STAT3 P40763 1/20 0.37
RCE1 Q9Y256 1/20 0.37
APAF1 O14727 1/20 0.37
HSP90AA1 P07900 1/20 0.37
NOD2 Q9HC29 1/20 0.37
NPC1 O15118 2/20 0.37
LMNA P02545 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5145846 0.81 MAPK1 (0.50) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL5143774 0.80 MAPK1 (0.49) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL28378701 0.80 MAPK1 (0.55) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL79875 0.79 SMN1; SMN2 (0.54) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL7786644 0.78 MAPK1 (0.47) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
Hydrochloric Acid SCHEMBL10575298 0.78 SMN1; SMN2 (0.53) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL12646310 0.77 MAPK1 (0.52) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
Acetic Acid SCHEMBL9815914 0.77 MAPK1 (0.58) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL7227225 0.76 MAPK1 (0.53) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL1636868 0.76 MAPK1 (0.60) MAPK1NPSR1SMN1; SMN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0304067-B1 Silver halide color photographic light-sensitive material containing epoxy compound FUJI PHOTO FILM CO LTD (JP) 1993-11-10 EP disclosed
US-5183731-A Storage stability yellow images; heat and water resistant, colorfastness FUJI PHOTO FILM CO., LTD. (JP) 1993-02-02 US disclosed
US-5104782-A Silver halide color photographic material containing a pyrazoloazole based coupler and having excellent color reproduction characteristics and which provides images having excellent light fastness FUJI PHOTO FILM CO., LTD. (JP) 1992-04-14 US disclosed