SCHEMBL9511779

SCHEMBL9511779

CCCCCCCC[C@H]1CC[C@H]([C@H]2CC[C@H](C=Cc3ccc(OCC(F)(F)F)cc3)CC2)CC1

nearest known ligand 0.33

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAOB P27338 4/20 0.33
LIPE Q05469 4/20 0.33
AHR P35869 1/20 0.33
CYP1A1 P04798 2/20 0.32
CYP1B1 Q16678 2/20 0.32
CHRNB2 P17787 1/20 0.32
CHRNB4 P30926 1/20 0.32
CHRNA3 P32297 1/20 0.32
CHRNA7 P36544 1/20 0.32
CHRNA4 P43681 1/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HPGD P15428 1/20 0.31
PTGES O14684 1/20 0.31
PPARA Q07869 1/20 0.31
LSS P48449 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9515542 1.00 MAOB (0.33) MAOBLIPEAHRCYP1A1CYP1B1
SCHEMBL9513687 1.00 MAOB (0.33) MAOBLIPEAHRCYP1A1CYP1B1
SCHEMBL9511763 0.99 MAOB (0.34) MAOBLIPEAHRCYP1A1CYP1B1
SCHEMBL9513232 0.96 LIPE (0.35) MAOBLIPEAHRCYP1A1CYP1B1
SCHEMBL9513215 0.92 MAOB (0.32) MAOBAHRHPGDPTGES
SCHEMBL9513126 0.92 MAOB (0.32) MAOBAHRHPGDPTGES
SCHEMBL9513681 0.92 MAOB (0.32) MAOBAHRHPGDPTGES
SCHEMBL9512220 0.91 LIPE (0.37) MAOBLIPECYP1A1CYP1B1CHRNB2
SCHEMBL9514440 0.90 MAOB (0.33) MAOBAHRHPGDPTGES
SCHEMBL9513281 0.90 MAOB (0.31) MAOBAHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0387315-B1 FLUORINATED ALKOXYL COMPOUNDS MERCK PATENT GMBH (DE) 1993-12-08 EP disclosed
EP-0387315-A1 FLUORINATED ALKOXYL COMPOUNDS. MERCK PATENT GMBH (DE) 1990-09-19 EP disclosed
WO-1990001021-A1 FLUORINATED ALKOXYL COMPOUNDS MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1990-02-08 WO disclosed