SCHEMBL9511939

SCHEMBL9511939

O=C(O)N(c1ccccc1)c1cc(Cl)ccc1Cl

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 2/20 0.44
ALDH1A1 P00352 2/20 0.43
TP53 P04637 1/20 0.43
KDM4E B2RXH2 1/20 0.43
TSHR P16473 1/20 0.43
CASP1 P29466 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
KMT2A Q03164 7/20 0.42
MEN1 O00255 6/20 0.42
SIGMAR1 Q99720 2/20 0.42
POLB P06746 2/20 0.42
NPC1 O15118 2/20 0.42
RAB9A P51151 2/20 0.42
HTT P42858 1/20 0.42
CACNA2D1 P54289 1/20 0.41
CACNA1B Q00975 1/20 0.41
CACNB1 Q02641 1/20 0.41
CACNA1C Q13936 1/20 0.41
GAA P10253 2/20 0.40
HPGD P15428 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2095804 0.86 FSCN1 (0.49) NPSR1ALDH1A1TP53KDM4ETSHR
SCHEMBL2092885 0.82 NPSR1 (0.50) NPSR1ALDH1A1TP53SMN1; SMN2KMT2A
SCHEMBL16513269 0.82 FDFT1 (0.43) NPSR1ALDH1A1TP53KDM4EKMT2A
SCHEMBL25252105 0.80 PPARA (0.42) NPSR1ALDH1A1TP53TSHRCASP1
SCHEMBL14300684 0.80 MAPT (0.47) ALDH1A1TP53KDM4ETSHRSMN1; SMN2
SCHEMBL2096920 0.77 NPSR1 (0.54) NPSR1ALDH1A1TSHRSMN1; SMN2KMT2A
SCHEMBL2094701 0.77 NPSR1 (0.48) NPSR1ALDH1A1SMN1; SMN2KMT2AMEN1
SCHEMBL1263260 0.76 ALDH1A1 (0.42) NPSR1ALDH1A1KDM4EKMT2AMEN1
SCHEMBL2092099 0.75 NPSR1 (0.47) NPSR1ALDH1A1TP53TSHRCASP1
SCHEMBL2091976 0.75 NPSR1 (0.47) NPSR1ALDH1A1TSHRKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4996339-A Colorless ORIENT CHEMICAL INDUSTRIES, LTD. (JP) 1991-02-26 US claimed
US-4855208-A Toner for developing electrostatic latent images ORIENT CHEMICAL INDUSTRIES LTD. (JP) 1989-08-08 US claimed
EP-0298388-B1 A toner for developing electrostatic latent images and a method of preparing the toner ORIENT CHEMICAL IND (JP) 1993-12-22 EP disclosed
US-4996339-A Colorless ORIENT CHEMICAL INDUSTRIES, LTD. (JP) 1991-02-26 US disclosed
US-4855208-A Toner for developing electrostatic latent images ORIENT CHEMICAL INDUSTRIES LTD. (JP) 1989-08-08 US disclosed
EP-0298388-A2 A toner for developing electrostatic latent images and a method of preparing the toner ORIENT CHEMICAL INDUSTRIES, LTD. (JP) 1989-01-11 EP disclosed