Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 10/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.46 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9509329 | 0.95 | ALDH1A1 (0.51) | ACACBALDH1A1MEN1USP2LMNA | |
| SCHEMBL10512628 | 0.94 | ALDH1A1 (0.54) | ACACBALDH1A1MEN1USP2LMNA | |
| SCHEMBL9512388 | 0.94 | ALDH1A1 (0.54) | ACACBALDH1A1MEN1USP2LMNA | |
| SCHEMBL9511398 | 0.94 | ALDH1A1 (0.54) | ACACBALDH1A1MEN1USP2LMNA | |
| SCHEMBL9512284 | 0.90 | ACACB (0.49) | ACACBALDH1A1 | |
| SCHEMBL9508928 | 0.89 | ACACB (0.50) | ACACBALDH1A1MEN1USP2LMNA | |
| SCHEMBL7508411 | 0.88 | ACACB (0.57) | ACACBMAPTRAB9AL3MBTL1 | |
| SCHEMBL9508901 | 0.88 | MEN1 (0.57) | ACACBALDH1A1MEN1USP2LMNA | |
| SCHEMBL9512255 | 0.87 | ACACB (0.45) | ACACBALDH1A1MEN1USP2LMNA | |
| SCHEMBL9509250 | 0.84 | ALDH1A1 (0.54) | ACACBALDH1A1MEN1USP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0308438-B1 | LIQUID CRYSTAL PHASE CONTAINING TOLANES | MERCK PATENT GmbH (DE) | 1993-09-29 | — | — | EP | disclosed |
| EP-0308438-A1 | Liquid crystal phase containing tolanes. | MERCK PATENT GMBH (DE) | 1989-03-29 | — | — | EP | disclosed |
| WO-1988007514-A1 | TOLANES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1988-10-06 | — | — | WO | disclosed |