Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 2/20 | 0.36 |
| ▸ | APLNR | P35414 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 6/20 | 0.35 |
| ▸ | CTSS | P25774 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29255570 | 1.00 | CYP1A2 (0.41) | CYP1A2CYP2C9CYP2C19HTTCA1 | |
| SCHEMBL10434800 | 0.80 | MAPK1 (0.39) | SMN1; SMN2 | |
| SCHEMBL7865687 | 0.78 | CTSK (0.42) | CYP1A2CYP2C9CYP2C19HTTCA1 | |
| SCHEMBL29254920 | 0.77 | PPARA (0.53) | CTSLCTSKCTSS | |
| SCHEMBL4555890 | 0.75 | CTSK (0.46) | CA1CA2CA7CTSLAPLNR | |
| SCHEMBL26656068 | 0.74 | CA1 (0.41) | CYP1A2CYP2C9CYP2C19HTTCA1 | |
| SCHEMBL26656061 | 0.74 | CA1 (0.41) | CYP1A2CYP2C9CYP2C19HTTCA1 | |
| SCHEMBL8211606 | 0.71 | CYP1A2 (0.62) | CYP1A2CYP2C9CYP2C19HTTCA1 | |
| SCHEMBL5147736 | 0.71 | CYP1A2 (0.62) | CYP1A2CYP2C9CYP2C19HTTCA1 | |
| SCHEMBL16245194 | 0.71 | CYP1A2 (0.54) | CYP1A2CYP2C9CYP2C19HTTCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0363994-B1 | (2R,3S,4S)-ALPHA-(CARBOXYCYCLOPROPYL)GLYCINE | SUNTORY LIMITED (JP) | 1993-09-22 | — | — | EP | disclosed |
| US-5068412-A | Nervous system disorders such as treatment of epilepsy or Huntington's chorea | SUNTORY LIMITED (JP) | 1991-11-26 | — | — | US | disclosed |