Dymanthine

Dymanthine

SCHEMBL9512573

CCCCCCCCCCCCCCCCCCN(C)C.CCCCCCS(=O)(=O)O

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 6/20 0.60
THRB P10828 6/20 0.48
THRA P10827 1/20 0.48
EPHX2 P34913 1/20 0.46
ALDH1A1 P00352 1/20 0.44
TSHR P16473 1/20 0.44
FAAH O00519 2/20 0.43
LYPLA1 O75608 2/20 0.42
LYPLA2 O95372 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5605734 1.00 DNM1 (0.60) DNM1THRBTHRAEPHX2ALDH1A1
Dymanthine SCHEMBL10655424 1.00 DNM1 (0.60) DNM1THRBTHRAEPHX2ALDH1A1
SCHEMBL10653894 1.00 DNM1 (0.60) DNM1THRBTHRAEPHX2ALDH1A1
SCHEMBL10657460 1.00 DNM1 (0.60) DNM1THRBTHRAEPHX2ALDH1A1
SCHEMBL4768819 0.96 DNM1 (0.60) DNM1THRBTHRAEPHX2ALDH1A1
Dymanthine SCHEMBL1133868 0.96 DNM1 (0.60) DNM1THRBTHRAEPHX2ALDH1A1
Hexadecane SCHEMBL26133982 0.94 DNM1 (0.56) DNM1THRBTHRAEPHX2ALDH1A1
SCHEMBL16395985 0.93 DNM1 (0.52) DNM1THRBTHRAEPHX2ALDH1A1
SCHEMBL20597793 0.92 DNM1 (0.60) DNM1THRBTHRAEPHX2ALDH1A1
SCHEMBL7559165 0.92 DNM1 (0.60) DNM1THRBTHRAEPHX2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0350407-B1 SOLID-PHASE REAGENT FOR THE COVALENT FIXATION OF AN AMINATED BIOLOGICAL LIGAND, ITS PREPARATION AND USE BIO MERIEUX Société anonyme dite: (FR) 1993-09-22 EP disclosed
EP-0350407-A1 Solid-phase reagent for the covalent fixation of an aminated biological ligand, its preparation and use BIO MERIEUX Société anonyme dite: (FR) 1990-01-10 EP disclosed
EP-0177376-B1 SULPHOBETAIN SURFACTANTS, THEIR PREPARATION AND THEIR USE, ESPECIALLY IN THE ENHANCED RECOVERY OF PETROLEUM Institut Français du Pétrole (FR) 1988-10-12 EP disclosed
US-4704229-A ZWITTERIONS INSTITUT FRANCAIS DU PETROLE (FR) 1987-11-03 US disclosed
EP-0177376-A1 Sulphobetain surfactants, their preparation and their use, especially in the enhanced recovery of petroleum Institut Français du Pétrole (FR) 1986-04-09 EP disclosed