Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.32 |
| ▸ | PTGDR | Q13258 | 4/20 | 0.32 |
| ▸ | CCR2 | P41597 | 1/20 | 0.32 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.31 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.31 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CFTR | P13569 | 1/20 | 0.31 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7410883 | 0.70 | HSD17B10 (0.36) | HSD17B10MAPTKDM4ESERPINE1PTGDR2 | |
| SCHEMBL5769073 | 0.70 | AKT1 (0.33) | — | |
| SCHEMBL7424445 | 0.70 | HSD17B10 (0.36) | HSD17B10MAPTKDM4ESERPINE1PTGDR2 | |
| SCHEMBL7413425 | 0.70 | HSD17B10 (0.36) | HSD17B10MAPTKDM4ESERPINE1PTGDR2 | |
| SCHEMBL9249778 | 0.68 | AKR1C4 (0.53) | HSD17B10MAPTKDM4ESERPINE1PTGDR2 | |
| SCHEMBL7325572 | 0.65 | FFAR4 (0.36) | AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL669624 | 0.64 | FFAR4 (0.38) | AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL2432528 | 0.64 | FFAR4 (0.49) | MAPTAKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL7312361 | 0.63 | HSD17B10 (0.37) | HSD17B10MAPTKDM4ESERPINE1PTGDR2 | |
| SCHEMBL7312354 | 0.63 | HSD17B10 (0.37) | HSD17B10MAPTKDM4ESERPINE1PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0559656-A1 | PROCESS FOR PREPARING MULTICYCLIC OXY-CONTAINING RING COMPONENTS | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1993-09-15 | — | — | EP | disclosed |
| WO-1992009592-A1 | PROCESS FOR PREPARING MULTICYCLIC OXY-CONTAINING RING COMPONENTS | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1992-06-11 | — | — | WO | disclosed |