Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9512819 | 0.84 | HMGCR (0.51) | GLRA1HMGCR | |
| SCHEMBL8780169 | 0.84 | HMGCR (0.53) | GLRA1HMGCR | |
| SCHEMBL9516080 | 0.78 | GLRA1 (0.50) | GLRA1 | |
| SCHEMBL8855126 | 0.75 | MGAM (0.44) | GLRA1HMGCR | |
| SCHEMBL13508914 | 0.74 | THRB (0.44) | — | |
| SCHEMBL9857596 | 0.72 | GCGR (0.41) | — | |
| SCHEMBL9516053 | 0.72 | CA1 (0.39) | — | |
| SCHEMBL13508907 | 0.71 | MAPT (0.40) | — | |
| SCHEMBL8854960 | 0.71 | GLRA1 (0.44) | GLRA1 | |
| SCHEMBL8854947 | 0.71 | MAOB (0.39) | GLRA1HMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0341681-B1 | 6-Phenoxymethyl-4-hydroxytetrahydropyran-2-ones and 6-thiophenoxymethyl-4-hydroxytetrahydropyran-2-ones, the corresponding dihydrocarboxylic-acid derivatives, salts and esters, process for preparing these compounds, their use as medicines, pharmaceutical compositions and phenols and thiophenols | HOECHST AG (DE) | 1993-12-29 | — | — | EP | disclosed |
| US-5166171-A | Compounds for treatment of artheriosclerosis and hypercholesterolemia | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-11-24 | — | — | US | disclosed |
| EP-0341681-A2 | 6-Phenoxymethyl-4-hydroxytetrahydropyran-2-ones and 6-thiophenoxymethyl-4-hydroxytetrahydropyran-2-ones, the corresponding dihydrocarboxylic-acid derivatives, salts and esters, process for preparing these compounds, their use as medicines, pharmaceutical compositions and phenols and thiophenols | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-11-15 | — | — | EP | disclosed |