Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | FDPS | P14324 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.35 |
| ▸ | TUBB | P07437 | 1/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.35 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.35 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.35 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.35 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.35 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.35 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.35 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.35 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.35 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4159665 | 0.81 | ALDH1A1 (0.36) | KDM4EALDH1A1L3MBTL1POLBTUBB4A | |
| SCHEMBL7993684 | 0.81 | ALDH1A1 (0.54) | KDM4EALDH1A1L3MBTL1POLBFDPS | |
| SCHEMBL207440 | 0.79 | KDM4E (0.59) | KDM4EALDH1A1L3MBTL1POLBFDPS | |
| SCHEMBL29501241 | 0.79 | KDM4E (0.59) | KDM4EALDH1A1L3MBTL1POLBFDPS | |
| SCHEMBL933951 | 0.77 | KDM4E (0.57) | KDM4EALDH1A1L3MBTL1POLBFDPS | |
| SCHEMBL27740854 | 0.75 | GAA (0.43) | KDM4EALDH1A1L3MBTL1FDPSNPSR1 | |
| SCHEMBL25281866 | 0.74 | KDM4E (0.54) | KDM4EALDH1A1L3MBTL1POLBFDPS | |
| SCHEMBL30385228 | 0.74 | KDM4E (0.54) | KDM4EALDH1A1L3MBTL1POLBFDPS | |
| SCHEMBL29935624 | 0.74 | KDM4E (0.54) | KDM4EALDH1A1L3MBTL1POLBFDPS | |
| SCHEMBL20489821 | 0.74 | KDM4E (0.54) | KDM4EALDH1A1L3MBTL1POLBFDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0411364-B1 | PROCESS FOR THE PREPARATION OF CHLORINATED NICOTINE-ALDEHYDES | BAYER AG (DE) | 1993-10-06 | — | — | EP | disclosed |
| US-5051513-A | Preparation of chlorinated nicotinaldehydes | BAYER AKTIENGESELLSCHAFT (DE) | 1991-09-24 | — | — | US | disclosed |