Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | TOP1 | P11387 | 1/20 | 0.42 |
| ▸ | TOP2A | P11388 | 2/20 | 0.41 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11179751 | 0.88 | KMT2A (0.52) | KDM4EALDH1A1POLBHSP90AA1RXFP1 | |
| SCHEMBL500816 | 0.84 | KDM4E (0.61) | KDM4EALDH1A1POLBHSP90AA1RXFP1 | |
| SCHEMBL30843076 | 0.84 | KDM4E (0.61) | KDM4EALDH1A1POLBHSP90AA1RXFP1 | |
| SCHEMBL500481 | 0.84 | KDM4E (0.69) | KDM4EALDH1A1POLBHSP90AA1RXFP1 | |
| SCHEMBL9512927 | 0.84 | STAT3 (0.37) | KDM4EALDH1A1POLBHSP90AA1RXFP1 | |
| SCHEMBL7011663 | 0.83 | KDM4E (0.58) | KDM4EALDH1A1POLBHSP90AA1RXFP1 | |
| SCHEMBL10681198 | 0.82 | KDM4E (0.51) | KDM4EALDH1A1POLBHSP90AA1RXFP1 | |
| SCHEMBL11185169 | 0.82 | KDM4E (0.60) | KDM4EALDH1A1POLBHSP90AA1RXFP1 | |
| Fluoride SCHEMBL6756478 | 0.82 | KDM4E (0.59) | KDM4EALDH1A1POLBHSP90AA1RXFP1 | |
| Oxalic Acid SCHEMBL27853160 | 0.81 | KDM4E (0.58) | KDM4EALDH1A1POLBHSP90AA1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563733-A1 | Use of 7-oxo-7H-pyrido(1,2,3-de)(1,4)benzoxacin-6-carboxylic acid- and esters for the manufacture of a medicament for the treatment of viral diseases | BAYER AG (DE) | 1993-10-06 | — | — | EP | disclosed |
| EP-0563732-A1 | 7-oxo-7H-pyrido(1,2,3-de)(1,4)benzoxazinecarboxylic acids and esters and their use as antiviral agents | BAYER AG (DE) | 1993-10-06 | — | — | EP | disclosed |