Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | TOP1 | P11387 | 1/20 | 0.31 |
| ▸ | TOP2A | P11388 | 1/20 | 0.30 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6217745 | 0.85 | KDM4E (0.45) | STAT3KDM4EKMT2AALDH1A1POLB | |
| SCHEMBL9512924 | 0.84 | KDM4E (0.51) | STAT3KDM4EKMT2AALDH1A1POLB | |
| SCHEMBL6213206 | 0.81 | KDM4E (0.38) | STAT3KDM4EKMT2AALDH1A1POLB | |
| SCHEMBL9513060 | 0.76 | STAT3 (0.36) | STAT3KDM4EKMT2AALDH1A1POLB | |
| SCHEMBL6214790 | 0.76 | KDM4E (0.49) | STAT3KDM4EKMT2AALDH1A1POLB | |
| SCHEMBL11259437 | 0.76 | KDM4E (0.44) | STAT3KDM4EKMT2AALDH1A1POLB | |
| SCHEMBL6213036 | 0.75 | STAT3 (0.38) | STAT3KDM4EKMT2AALDH1A1POLB | |
| SCHEMBL6212721 | 0.75 | STAT3 (0.38) | STAT3KDM4EKMT2AALDH1A1POLB | |
| SCHEMBL8136263 | 0.75 | TOP2A (0.45) | STAT3KDM4EKMT2AALDH1A1POLB | |
| SCHEMBL11261125 | 0.75 | KDM4E (0.50) | STAT3KDM4EKMT2AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563733-A1 | Use of 7-oxo-7H-pyrido(1,2,3-de)(1,4)benzoxacin-6-carboxylic acid- and esters for the manufacture of a medicament for the treatment of viral diseases | BAYER AG (DE) | 1993-10-06 | — | — | EP | disclosed |
| EP-0563732-A1 | 7-oxo-7H-pyrido(1,2,3-de)(1,4)benzoxazinecarboxylic acids and esters and their use as antiviral agents | BAYER AG (DE) | 1993-10-06 | — | — | EP | disclosed |