SCHEMBL9512930

SCHEMBL9512930

CCN(c1ccc(C)cc1)c1ccc(Nc2ccc(Nc3ccccc3)cc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.64
NR3C2 P08235 1/20 0.53
HSD17B10 Q99714 3/20 0.46
TDP1 Q9NUW8 3/20 0.46
ALDH1A1 P00352 2/20 0.46
ALOX15 P16050 2/20 0.46
TSHR P16473 2/20 0.46
ALOX12 P18054 2/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
PTGS1 P23219 1/20 0.46
SLC6A2 P23975 1/20 0.46
MAPK1 P28482 1/20 0.46
PTGS2 P35354 1/20 0.46
HTR2B P41595 1/20 0.46
GAA P10253 3/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
NPSR1 Q6W5P4 1/20 0.44
MAPT P10636 4/20 0.44
POLB P06746 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17753337 0.93 HPGD (0.55) HPGDNR3C2HSD17B10TDP1ALDH1A1
SCHEMBL4893330 0.85 HPGD (0.75) HPGDHSD17B10TDP1ALDH1A1ALOX15
SCHEMBL5609630 0.85 NR3C2 (0.53) NR3C2ALDH1A1TSHRALOX12L3MBTL1
SCHEMBL12955888 0.83 HPGD (0.72) HPGDHSD17B10TDP1ALDH1A1ALOX15
SCHEMBL27315667 0.81 GAA (0.48) HPGDNR3C2HSD17B10TDP1ALDH1A1
SCHEMBL21146865 0.81 NR3C2 (0.50) NR3C2TDP1ALDH1A1TSHRALOX12
SCHEMBL12700477 0.81 HPGD (0.68) HPGDHSD17B10TDP1ALDH1A1ALOX15
SCHEMBL12955812 0.81 HPGD (0.68) HPGDHSD17B10TDP1ALDH1A1ALOX15
SCHEMBL22044806 0.81 HPGD (0.68) HPGDHSD17B10TDP1ALDH1A1ALOX15
SCHEMBL17753334 0.81 HPGD (0.68) HPGDHSD17B10TDP1ALDH1A1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0273418-B1 Heat-sensitive recording material using chromeno compound KANZAKI PAPER MFG CO LTD (JP) 1993-11-24 EP disclosed
US-4803193-A COLORFASTNESS; READABLE BY OPTICAL CHARACTER-READING DEVICES KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1989-02-07 US disclosed
EP-0273418-A2 Heat-sensitive recording material using chromeno compound KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1988-07-06 EP disclosed