Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 3/20 | 0.41 |
| ▸ | CNR2 | P34972 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5609630 | 0.96 | NR3C2 (0.53) | NR3C2CYP2C19MAPTALDH1A1CYP1A2 | |
| SCHEMBL16408145 | 0.91 | NR3C2 (0.56) | NR3C2CYP2C19MAPTALDH1A1CYP1A2 | |
| SCHEMBL17753337 | 0.89 | HPGD (0.55) | NR3C2CYP2C19MAPTALDH1A1KDM4E | |
| SCHEMBL7149333 | 0.87 | NR3C2 (0.60) | NR3C2CYP2C19MAPTALDH1A1CYP1A2 | |
| SCHEMBL16707568 | 0.87 | ALDH1A1 (0.56) | CYP2C19MAPTALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL6139963 | 0.87 | ALDH1A1 (0.56) | CYP2C19MAPTALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL12154508 | 0.87 | ALDH1A1 (0.56) | CYP2C19MAPTALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL13515157 | 0.87 | ALDH1A1 (0.56) | CYP2C19MAPTALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL13990423 | 0.87 | ALDH1A1 (0.56) | CYP2C19MAPTALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL43023 | 0.87 | ALDH1A1 (0.56) | CYP2C19MAPTALDH1A1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2692796-B1 | COMPOSITION | SUMITOMO CHEMICAL CO (JP) | 2019-07-10 | — | — | EP | disclosed |