SCHEMBL9512976

SCHEMBL9512976

CCN(Cc1ccccc1)c1ccc(Nc2ccc(Nc3ccccc3)cc2)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.70
CNR2 P34972 4/20 0.59
KMT2A Q03164 3/20 0.54
NOX1 Q9Y5S8 2/20 0.54
MEN1 O00255 2/20 0.54
NPC1 O15118 2/20 0.54
RAB9A P51151 2/20 0.54
NR1H2 P55055 1/20 0.54
NR1H3 Q13133 1/20 0.54
CYP2C19 P33261 1/20 0.53
KDM1A O60341 1/20 0.51
ALDH1A1 P00352 6/20 0.49
MAPT P10636 5/20 0.49
TDP1 Q9NUW8 5/20 0.49
KDM4E B2RXH2 4/20 0.49
MAPK1 P28482 4/20 0.49
HPGD P15428 3/20 0.49
LMNA P02545 3/20 0.49
NPY5R Q15761 1/20 0.49
MITF O75030 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9483764 0.89 CYP2C19 (0.60) TSHRCNR2KMT2ANOX1MEN1
SCHEMBL9514537 0.87 CYP2C19 (0.62) TSHRCNR2KMT2ANR1H2NR1H3
SCHEMBL141889 0.87 NPC1 (0.68) TSHRCNR2KMT2ANOX1MEN1
SCHEMBL9514595 0.87 NPC1 (0.68) TSHRCNR2KMT2ANOX1MEN1
SCHEMBL179996 0.83 TSHR (1.00) TSHRCNR2KMT2ANR1H2NR1H3
SCHEMBL28715878 0.82 MEN1 (0.62) TSHRCNR2KMT2ANOX1MEN1
SCHEMBL17460822 0.82 TSHR (0.81) TSHRCNR2KMT2AMEN1NPC1
Bromide SCHEMBL27967621 0.81 TSHR (0.96) TSHRCNR2KMT2ANR1H2NR1H3
Hydrochloric Acid SCHEMBL3672654 0.81 TSHR (0.96) TSHRCNR2KMT2ANR1H2NR1H3
SCHEMBL10803774 0.81 CNR2 (0.69) TSHRCNR2KMT2ANOX1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0273418-B1 Heat-sensitive recording material using chromeno compound KANZAKI PAPER MFG CO LTD (JP) 1993-11-24 EP disclosed
US-4803193-A COLORFASTNESS; READABLE BY OPTICAL CHARACTER-READING DEVICES KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1989-02-07 US disclosed
EP-0273418-A2 Heat-sensitive recording material using chromeno compound KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1988-07-06 EP disclosed