Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.68 |
| ▸ | RAB9A | P51151 | 4/20 | 0.68 |
| ▸ | MEN1 | O00255 | 3/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.68 |
| ▸ | KDM1A | O60341 | 1/20 | 0.63 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL141889 | 1.00 | NPC1 (0.68) | NPC1RAB9AMEN1KMT2ANOX1 | |
| SCHEMBL28715878 | 0.94 | MEN1 (0.62) | NPC1RAB9AMEN1KMT2ANOX1 | |
| SCHEMBL7664793 | 0.91 | ADRA2A (0.58) | NPC1RAB9AMEN1KMT2ANOX1 | |
| SCHEMBL9510729 | 0.89 | MEN1 (0.56) | NPC1RAB9AMEN1KMT2ANOX1 | |
| SCHEMBL9512976 | 0.87 | TSHR (0.70) | NPC1RAB9AMEN1KMT2ANOX1 | |
| SCHEMBL9508042 | 0.86 | MEN1 (0.53) | NPC1RAB9AMEN1KMT2ANOX1 | |
| SCHEMBL11733311 | 0.84 | MEN1 (0.51) | NPC1RAB9AMEN1KMT2ANOX1 | |
| SCHEMBL6566806 | 0.84 | MAPT (0.50) | NPC1RAB9AMEN1KMT2ANOX1 | |
| SCHEMBL11729511 | 0.83 | MAPT (0.54) | NPC1RAB9AMEN1KMT2ANOX1 | |
| SCHEMBL11171615 | 0.83 | ADRA2A (0.51) | NPC1RAB9AMEN1KMT2ANOX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273418-B1 | Heat-sensitive recording material using chromeno compound | KANZAKI PAPER MFG CO LTD (JP) | 1993-11-24 | — | — | EP | disclosed |
| US-4803193-A | COLORFASTNESS; READABLE BY OPTICAL CHARACTER-READING DEVICES | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1989-02-07 | — | — | US | disclosed |
| EP-0273418-A2 | Heat-sensitive recording material using chromeno compound | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1988-07-06 | — | — | EP | disclosed |