Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 6/20 | 0.51 |
| ▸ | CA2 | P00918 | 6/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | CA12 | O43570 | 2/20 | 0.51 |
| ▸ | CA9 | Q16790 | 2/20 | 0.51 |
| ▸ | CA4 | P22748 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9706226 | 0.86 | SMN1; SMN2 (0.60) | SMN1; SMN2RAB9AALDH1A1KMT2AMAPT | |
| SCHEMBL9705351 | 0.85 | SMN1; SMN2 (0.59) | CA1CA2SMN1; SMN2CA12CA9 | |
| SCHEMBL6029973 | 0.82 | SMN1; SMN2 (0.59) | SMN1; SMN2RAB9AALDH1A1PKMHTT | |
| SCHEMBL9705721 | 0.80 | CA1 (0.69) | CA1CA2CA12CA9CA4 | |
| SCHEMBL6856040 | 0.80 | CYP1A2 (0.54) | SMN1; SMN2ALDH1A1KMT2AMAPTHSD11B1 | |
| SCHEMBL9090227 | 0.79 | SMN1; SMN2 (0.61) | SMN1; SMN2RAB9AALDH1A1PKMHTT | |
| SCHEMBL19876826 | 0.79 | TDP1 (0.71) | SMN1; SMN2ALDH1A1KMT2AMAPTL3MBTL1 | |
| SCHEMBL8209122 | 0.79 | TDP1 (0.66) | SMN1; SMN2KMT2AMAPTL3MBTL1ALOX15 | |
| Hydrochloric Acid SCHEMBL9677581 | 0.78 | SMN1; SMN2 (0.59) | SMN1; SMN2RAB9AALDH1A1PKMHTT | |
| SCHEMBL2818579 | 0.77 | SMN1; SMN2 (0.68) | SMN1; SMN2ALDH1A1KMT2AMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563145-A1 | CHELATING AGENTS | NYCOMED AS (NO) | 1993-10-06 | — | — | EP | disclosed |
| WO-1992011232-A1 | CHELATING AGENTS | NYCOMED IMAGING AS (NO) | 1992-07-09 | — | — | WO | disclosed |