Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 2/20 | 0.56 |
| ▸ | CNR1 | P21554 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9090227 | 0.88 | SMN1; SMN2 (0.61) | SMN1; SMN2RAB9AALDH1A1HTTPKM | |
| Hydrochloric Acid SCHEMBL9677581 | 0.86 | SMN1; SMN2 (0.59) | SMN1; SMN2RAB9AALDH1A1HTTPKM | |
| SCHEMBL16353805 | 0.85 | SMN1; SMN2 (0.74) | SMN1; SMN2RAB9AALDH1A1HTTPKM | |
| SCHEMBL1694984 | 0.85 | RAB9A (0.62) | SMN1; SMN2RAB9AALDH1A1HTTCNR1 | |
| SCHEMBL2093615 | 0.84 | SMN1; SMN2 (0.59) | SMN1; SMN2RAB9AALDH1A1HTTPKM | |
| Hydrochloric Acid SCHEMBL7603529 | 0.83 | RAB9A (0.61) | SMN1; SMN2RAB9AALDH1A1HTTCNR1 | |
| SCHEMBL9369229 | 0.83 | SMN1; SMN2 (0.72) | SMN1; SMN2RAB9AALDH1A1HTTKMT2A | |
| SCHEMBL9513072 | 0.82 | CA1 (0.51) | SMN1; SMN2RAB9AALDH1A1HTTPKM | |
| SCHEMBL27263888 | 0.81 | RAB9A (0.58) | SMN1; SMN2RAB9AALDH1A1HTTPKM | |
| SCHEMBL12999538 | 0.81 | SMN1; SMN2 (0.61) | SMN1; SMN2RAB9AALDH1A1HTTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1478653-B1 | MACROLIDES WITH ANTIBACTERIAL ACTIVITY | BASILEA PHARMACEUTICA AG (CH) | 2014-07-02 | — | — | EP | disclosed |
| CN-101289483-B | Macrolides with antibacterial activity | BASILEA PHARMACEUTICA AG | 2012-06-20 | — | — | CN | disclosed |
| CN-101367854-B | Macrolides with antibacterial activity | BASILEA PHARMACEUTICA AG | 2010-12-29 | — | — | CN | disclosed |
| CN-100509833-C | Macrolides with antibacterial activity | BASILEA PHARMACEUTICA AG (CH) | 2009-07-08 | — | — | CN | disclosed |
| CN-101367854-A | Macrolides with antibacterial activity | BASILEA PHARMACEUTICA AG (CH) | 2009-02-18 | — | — | CN | disclosed |
| CN-101289483-A | Macrolides with antibacterial activity | BASILEA PHARMACEUTICA AG (CH) | 2008-10-22 | — | — | CN | disclosed |
| CN-101289484-A | Macrolides with antibacterial activity | BASILEA PHARMACEUTICA AG (CH) | 2008-10-22 | — | — | CN | disclosed |
| US-6995143-B2 | Macrolides with antibacterial activity | BASILEA PHARMACEUTICA AG (CH) | 2006-02-07 | — | — | US | disclosed |
| CN-1630661-A | Macrolides with antibacterial activity | BASILEA PHARMACEUTICA AG (CH) | 2005-06-22 | — | — | CN | disclosed |
| EP-1478653-A1 | MACROLIDES WITH ANTIBACTERIAL ACTIVITY | Basilea Pharmaceutica AG (CH) | 2004-11-24 | — | — | EP | disclosed |
| US-20030212011-A1 | Macrolides with antibacterial activity | BASILEA PHARMACEUTICA AG (CH) | 2003-11-13 | — | — | US | disclosed |
| WO-2003072588-A1 | MACROLIDES WITH ANTIBACTERIAL ACTIVITY | BASILEA PHARMACEUTICA AG (CH) | 2003-09-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030212011-A1 | Macrolides with antibacterial activity | MRPL21, RPS21, MRPS18A | SMN1; SMN2 2162/4885RAB9A 766/4885ALDH1A1 3345/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.