Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.58 |
| ▸ | PLA2G4B | P0C869 | 4/20 | 0.57 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.57 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.55 |
| ▸ | RARB | P10826 | 3/20 | 0.55 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.53 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9513090 | 0.99 | ALDH1A1 (0.58) | ALDH1A1HPGDTP53TSHRPTPN11 | |
| SCHEMBL9514148 | 0.87 | SMPD1 (0.54) | ALDH1A1HPGDPTPN11PLA2G2D | |
| SCHEMBL9513086 | 0.87 | SMPD1 (0.49) | ALDH1A1HPGDTP53TSHRPTPN11 | |
| SCHEMBL9513056 | 0.86 | PLA2G2D (0.58) | ALDH1A1HPGDTP53TSHRPTPN11 | |
| SCHEMBL9514125 | 0.86 | PLA2G2D (0.58) | ALDH1A1HPGDTP53TSHRPTPN11 | |
| SCHEMBL9515491 | 0.86 | PLA2G2D (0.58) | ALDH1A1HPGDTP53TSHRPTPN11 | |
| SCHEMBL9515443 | 0.85 | PLA2G2D (0.57) | ALDH1A1HPGDTP53TSHRPTPN11 | |
| SCHEMBL9516447 | 0.85 | PLA2G2D (0.57) | ALDH1A1HPGDTP53TSHRPTPN11 | |
| SCHEMBL9513108 | 0.85 | PLA2G2D (0.57) | ALDH1A1HPGDTP53TSHRPTPN11 | |
| SCHEMBL1199847 | 0.84 | ALDH1A1 (0.69) | ALDH1A1HPGDTP53TSHRPTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0308977-B1 | Anthracycline derivatives having inhibitory activity against reverse transcriptase of human immunodeficiency virus | ZAIDAN HOJIN BISEIBUTSU (JP) | 1993-12-08 | — | — | EP | disclosed |
| US-5003055-A | Anthracycline derivatives having inhibitory activity against reverse transcriptase of human immunodeficiency virus | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1991-03-26 | — | — | US | disclosed |
| EP-0308977-A2 | Anthracycline derivatives having inhibitory activity against reverse transcriptase of human immunodeficiency virus | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1989-03-29 | — | — | EP | disclosed |