Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9238784 | 0.92 | LMNA (0.59) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL9234116 | 0.88 | LMNA (0.60) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL8373426 | 0.87 | LMNA (0.59) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL10435790 | 0.86 | CYP2C19 (0.59) | LMNACYP2C19HIF1A | |
| SCHEMBL9239590 | 0.85 | LMNA (0.57) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL8380586 | 0.84 | LMNA (0.56) | LMNACYP2C19HIF1A | |
| SCHEMBL9236621 | 0.83 | LMNA (0.59) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL9231788 | 0.83 | CYP2C19 (0.69) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL9735793 | 0.82 | LMNA (0.61) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL5033214 | 0.82 | LMNA (0.61) | LMNACYP2C19HIF1AEGFRSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0357467-B1 | Non-ionic tri-iodobenzene compounds, and contrast agents containing same | GUERBET SA (FR) | 1993-12-08 | — | — | EP | claimed |
| US-5043152-A | Radiography | GUERBET S.A. (FR) | 1991-08-27 | — | — | US | claimed |
| EP-0357467-A1 | Non-ionic tri-iodobenzene compounds, and contrast agents containing same | GUERBET S.A. (FR) | 1990-03-07 | — | — | EP | claimed |
| EP-0357467-B1 | Non-ionic tri-iodobenzene compounds, and contrast agents containing same | GUERBET SA (FR) | 1993-12-08 | — | — | EP | disclosed |
| US-5043152-A | Radiography | GUERBET S.A. (FR) | 1991-08-27 | — | — | US | disclosed |