Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 4/20 | 0.51 |
| ▸ | DRD2 | P14416 | 4/20 | 0.45 |
| ▸ | DRD3 | P35462 | 3/20 | 0.45 |
| ▸ | HTR1D | P28221 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | FYN | P06241 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9305400 | 0.99 | GRIN2B (0.50) | GRIN2BDRD2DRD3HTR1DACHE | |
| SCHEMBL9513897 | 0.92 | GRIN2B (0.49) | GRIN2BDRD2DRD3HTR1DACHE | |
| Hydrochloric Acid SCHEMBL9304446 | 0.92 | GRIN2B (0.48) | GRIN2BDRD2DRD3HTR1DACHE | |
| SCHEMBL9513945 | 0.91 | GRIN2B (0.47) | GRIN2BDRD2DRD3HTR1DACHE | |
| Hydrochloric Acid SCHEMBL9304769 | 0.90 | GRIN2B (0.47) | GRIN2BDRD2DRD3HTR1DACHE | |
| SCHEMBL9514819 | 0.85 | GRIN2B (0.49) | GRIN2BDRD2DRD3HTR1DACHE | |
| Hydrochloric Acid SCHEMBL8766600 | 0.83 | GRIN2B (0.45) | GRIN2BDRD2DRD3HTR1DFYN | |
| SCHEMBL8765904 | 0.83 | ADRB3 (0.49) | GRIN2BDRD2DRD3FYN | |
| SCHEMBL9443702 | 0.83 | ADRB3 (0.56) | GRIN2BDRD2DRD3HTR1D | |
| Hydrochloric Acid SCHEMBL9443699 | 0.82 | ADRB3 (0.56) | GRIN2BDRD2DRD3HTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0383686-B1 | 2-AMINO-7-HYDROXYTETRALINE CARBOXYALKYL ETHERS | ELF SANOFI (FR) | 1993-08-04 | — | — | EP | claimed |
| EP-0383686-A1 | 2-Amino-7-hydroxytetraline carboxyalkyl ethers | ELF SANOFI (FR) | 1990-08-22 | — | — | EP | claimed |
| EP-0383686-B1 | 2-AMINO-7-HYDROXYTETRALINE CARBOXYALKYL ETHERS | ELF SANOFI (FR) | 1993-08-04 | — | — | EP | disclosed |
| EP-0383686-A1 | 2-Amino-7-hydroxytetraline carboxyalkyl ethers | ELF SANOFI (FR) | 1990-08-22 | — | — | EP | disclosed |