Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.65 |
| ▸ | RAB9A | P51151 | 5/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.65 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | RARB | P10826 | 3/20 | 0.57 |
| ▸ | LTA4H | P09960 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7506953 | 1.00 | NPC1 (0.65) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL7877116 | 1.00 | NPC1 (0.65) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL6534975 | 1.00 | NPC1 (0.65) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL7883583 | 0.92 | NPC1 (0.63) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL9228047 | 0.90 | NR5A1 (0.69) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL10574379 | 0.90 | NR5A1 (0.69) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL10337755 | 0.90 | NR5A1 (0.69) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL6255603 | 0.90 | NR5A1 (0.69) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL9343934 | 0.90 | NR5A1 (0.69) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL6254577 | 0.90 | NR5A1 (0.69) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0277815-B1 | Optically active-2-alkoxy-propyl ether and liquid crystal composition | CHISSO CORP (JP) | 1993-11-24 | — | — | EP | disclosed |
| US-5021191-A | Ferroelectricity display elements; extremely small redution in crystal temperature region | CHISSO CORPORATION (JP) | 1991-06-04 | — | — | US | disclosed |