Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.65 |
| ▸ | RAB9A | P51151 | 5/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.65 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | RARB | P10826 | 3/20 | 0.57 |
| ▸ | LTA4H | P09960 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7506953 | 1.00 | NPC1 (0.65) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL7877116 | 1.00 | NPC1 (0.65) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL9513828 | 1.00 | NPC1 (0.65) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL7883583 | 0.92 | NPC1 (0.63) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL9228047 | 0.90 | NR5A1 (0.69) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL10574379 | 0.90 | NR5A1 (0.69) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL10337755 | 0.90 | NR5A1 (0.69) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL6255603 | 0.90 | NR5A1 (0.69) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL9343934 | 0.90 | NR5A1 (0.69) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL6254577 | 0.90 | NR5A1 (0.69) | NPC1RAB9AKDM4ESMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6783812-B2 | USEFUL IN THE MANUFACTURE OF OPTICAL DEVICES; STABILITY | DISPLAYTECH, INC. | 2004-08-31 | — | — | US | disclosed |
| US-6737124-B2 | ESPECIALLY DISILANES | DISPLAYTECH, INC. | 2004-05-18 | — | — | US | disclosed |
| US-20030003245-A1 | Liquid crystal compounds having a silane tail with a perfluoroalkyl terminal portion | CITIZEN FINETECH MIYOTA CO., LTD. (JP) | 2003-01-02 | — | — | US | disclosed |
| US-20020130299-A1 | Alkyl silane liquid crystal compounds | CITIZEN FINEDEVICE CO., LTD. (JP) | 2002-09-19 | — | — | US | disclosed |
| US-6413448-B1 | ESTERS; DOPANTS; LONGER CHIRAL SMECTIC PHASE PITCH; HIGHER TILT ANGLE; LOWER VISCOSITY; CRYSTALLIZATION SUPPRESSION; IMPROVED SOLUBILITY; BROADER C* PHASE TEMPERATURE RANGE | DISPLAYTECH, INC. | 2002-07-02 | — | — | US | disclosed |
| WO-2000065801-A9 | CYCLOHEXYL- AND CYCLOHEXENYL-SUBSTITUTED LIQUID CRYSTALS WITH LOW BIREFRINGENCE | DISPLAYTECH INC (US) | 2001-04-12 | — | — | WO | disclosed |
| WO-2000065801-A1 | CYCLOHEXYL- AND CYCLOHEXENYL-SUBSTITUTED LIQUID CRYSTALS WITH LOW BIREFRINGENCE | DISPLAYTECH, INC. (US) | 2000-11-02 | — | — | WO | disclosed |
| EP-0606090-B1 | Mesomorphic compound, liquid crystal composition containing same, and liquid crystal device using same | CANON KK (JP) | 1997-10-29 | — | — | EP | disclosed |
| US-5589103-A | Mesomorphic compound, liquid crystal composition containing same, and liquid crystal device using same | CANON KABUSHIKI KAISHA (JP) | 1996-12-31 | — | — | US | disclosed |
| EP-0606090-A1 | Mesomorphic compound, liquid crystal composition containing same, and liquid crystal device using same | CANON KABUSHIKI KAISHA (JP) | 1994-07-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030003245-A1 | Liquid crystal compounds having a silane tail with a perfluoroalkyl terminal portion | FFAR3, FFAR1, LPAR1 | NPC1 393/4885RAB9A 1832/4885KDM4E 2549/4885 |
| US-20020130299-A1 | Alkyl silane liquid crystal compounds | SMURF1, SMURF2, DSTN | NPC1 2373/4885RAB9A 3181/4885KDM4E 651/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.