Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAP | Q12884 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 8/20 | 0.65 |
| ▸ | MAPT | P10636 | 5/20 | 0.65 |
| ▸ | APEX1 | P27695 | 4/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.65 |
| ▸ | NR1I2 | O75469 | 4/20 | 0.62 |
| ▸ | ALB | P02768 | 1/20 | 0.62 |
| ▸ | PPARG | P37231 | 1/20 | 0.62 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.62 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.62 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.62 |
| ▸ | HTR2C | P28335 | 1/20 | 0.61 |
| ▸ | APAF1 | O14727 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9513891 | 1.00 | FAP (0.67) | FAPTDP1MAPTAPEX1ALDH1A1 | |
| SCHEMBL10472780 | 0.93 | MAPT (0.72) | FAPTDP1MAPTAPEX1ALDH1A1 | |
| SCHEMBL10472778 | 0.93 | MAPT (0.72) | FAPTDP1MAPTAPEX1ALDH1A1 | |
| Cefcapene SCHEMBL419455 | 0.92 | FAP (0.77) | FAPTDP1MAPTAPEX1ALDH1A1 | |
| Cefcapene SCHEMBL419454 | 0.92 | FAP (0.77) | FAPTDP1MAPTAPEX1ALDH1A1 | |
| Cefcapene SCHEMBL419453 | 0.92 | FAP (0.77) | FAPTDP1MAPTAPEX1ALDH1A1 | |
| Cefcapene SCHEMBL2828959 | 0.92 | FAP (0.79) | FAPTDP1MAPTAPEX1ALDH1A1 | |
| Cefcapene SCHEMBL27739649 | 0.92 | FAP (0.76) | FAPTDP1MAPTAPEX1ALDH1A1 | |
| Cefcapene SCHEMBL2828956 | 0.92 | FAP (0.79) | FAPTDP1MAPTAPEX1ALDH1A1 | |
| SCHEMBL9513927 | 0.92 | NR1I2 (0.73) | FAPTDP1MAPTAPEX1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0136721-B1 | Carboxyalkenamidocephalosporins | SHIONOGI & CO (JP) | 1993-12-29 | — | — | EP | claimed |
| US-4634697-A | Carboxyalkenamidocephalosporins | SHIONOGI & CO., LTD. (JP) | 1987-01-06 | — | — | US | claimed |
| EP-0136721-A2 | Carboxyalkenamidocephalosporins | SHIONOGI & CO., LTD. (JP) | 1985-04-10 | — | — | EP | claimed |
| EP-0136721-B1 | Carboxyalkenamidocephalosporins | SHIONOGI & CO (JP) | 1993-12-29 | — | — | EP | disclosed |
| US-4912224-A | Containing a aminothiazolyl or aminothiadiazolyl ring | SHIONOGI & CO., LTD. (JP) | 1990-03-27 | — | — | US | disclosed |
| US-4748170-A | Carboxyalkenamidocephalosporins | SHIONOGI & CO., LTD. (JP) | 1988-05-31 | — | — | US | disclosed |
| US-4634697-A | Carboxyalkenamidocephalosporins | SHIONOGI & CO., LTD. (JP) | 1987-01-06 | — | — | US | disclosed |
| EP-0136721-A2 | Carboxyalkenamidocephalosporins | SHIONOGI & CO., LTD. (JP) | 1985-04-10 | — | — | EP | disclosed |