SCHEMBL9514017

SCHEMBL9514017

O=C(Cl)c1cc(N2C(=O)C3=C(CCCC3)C2=O)c(F)cc1I

nearest known ligand 0.54

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GRM7 Q14831 4/20 0.48
GRM4 Q14833 4/20 0.48
GRM1 Q13255 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9517785 0.88 GRM7 (0.47) GRM7GRM4GRM1
SCHEMBL10758624 0.87 GRM7 (0.46) GRM7GRM4GRM1
SCHEMBL9765563 0.85 GRM7 (0.47) GRM7GRM4GRM1
SCHEMBL9517807 0.81 GRM7 (0.42) GRM7GRM4GRM1
SCHEMBL9516398 0.80 GRM7 (0.44) GRM7GRM4GRM1
SCHEMBL10765350 0.77 GRM7 (0.39) GRM7GRM4
SCHEMBL29077296 0.77 GRM7 (0.47) GRM7GRM4GRM1
SCHEMBL10935535 0.76 GRM7 (0.48) GRM7GRM4GRM1
SCHEMBL9736832 0.76 GRM7 (0.46) GRM7GRM4GRM1
SCHEMBL9516380 0.74 GRM7 (0.42) GRM7GRM4GRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0303573-B1 PYRROLIDINE-2,5 DIONES AND 4,5,6,7-TETRAHYDROISO-INDOLE-1,3 DIONES CIBA-GEIGY AG (CH) 1993-06-09 EP disclosed
US-4919704-A PREEMERGENCE AND POSTEMERGENCE HERBICIDES CIBA-GEIGY CORPORATION (US) 1990-04-24 US disclosed
EP-0303573-A1 Pyrrolidine-2,5 diones and 4,5,6,7-tetrahydroiso-indole-1,3 diones CIBA-GEIGY AG (CH) 1989-02-15 EP disclosed