SCHEMBL9765563

SCHEMBL9765563

O=C(Cl)c1cc(N2C(=O)C3=C(CCCC3)C2=O)c(F)cc1Cl

nearest known ligand 0.68

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GRM7 Q14831 4/20 0.47
GRM4 Q14833 4/20 0.47
GRM1 Q13255 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29077296 0.89 GRM7 (0.47) GRM7GRM4GRM1
SCHEMBL10758624 0.89 GRM7 (0.46) GRM7GRM4GRM1
SCHEMBL9736832 0.88 GRM7 (0.46) GRM7GRM4GRM1
SCHEMBL10935535 0.88 GRM7 (0.48) GRM7GRM4GRM1
SCHEMBL10765350 0.87 GRM7 (0.39) GRM7GRM4
SCHEMBL9514017 0.85 GRM7 (0.48) GRM7GRM4GRM1
SCHEMBL25480853 0.82 GRM7 (0.42) GRM7GRM4
SCHEMBL9517807 0.82 GRM7 (0.42) GRM7GRM4GRM1
SCHEMBL11201432 0.81 PPOX (0.45) GRM7GRM4
SCHEMBL10421169 0.81 POLB (0.36) GRM7GRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5034048-A Plant growth regulators, 5(tetrahydrophthalamido)benzoic acid derivatives for controlling weeds CIBA-GEIGY CORPORATION (US) 1991-07-23 US disclosed
US-5007951-A Pre- or postemergent herbicides for use with crops CIBA-GEIGY CORPORATION (US) 1991-04-16 US disclosed
US-4917721-A TETRAHYDROPHTHALIMIDO BENZOIC ACID THIOESTERS CIBA-GEIGY CORPORATION (US) 1990-04-17 US disclosed
EP-0338987-A1 5-(N-3,4,6-tetrahydrophthalimido)benzoic-acid thiol esters as selective herbicides CIBA-GEIGY AG (CH) 1989-10-25 EP disclosed