⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1824 | 0.69 | — | — | |
| SCHEMBL2109592 | 0.69 | — | — | |
| SCHEMBL9514024 | 0.68 | — | — | |
| SCHEMBL11628284 | 0.67 | TP53 (0.41) | — | |
| SCHEMBL3752904 | 0.65 | — | — | |
| SCHEMBL3752663 | 0.65 | — | — | |
| SCHEMBL4033784 | 0.65 | — | — | |
| SCHEMBL2110251 | 0.65 | — | — | |
| SCHEMBL8018534 | 0.65 | — | — | |
| SCHEMBL28202 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0256763-B1 | Process for azetidinones | UNIV NOTRE DAME DU LAC (US) | 1993-12-08 | — | — | EP | disclosed |
| US-4751296-A | WITH POSITIVE HALOGEN IN THE PRESENCE OF WEAK BASE | UNIVERSITY OF NOTRE DAME DU LAC (US) | 1988-06-14 | — | — | US | disclosed |
| EP-0256763-A1 | Process for azetidinones | THE UNIVERSITY OF NOTRE DAME DU LAC (US) | 1988-02-24 | — | — | EP | disclosed |