SCHEMBL9514042

SCHEMBL9514042

C=CC(Cc1ccccc1)C(=O)Cl

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.47
ALPI P09923 1/20 0.44
PKM P14618 1/20 0.44
PTGS1 P23219 1/20 0.44
XIAP P98170 1/20 0.44
SLC7A5 Q01650 1/20 0.44
MDM2 Q00987 1/20 0.43
ALDH1A1 P00352 2/20 0.42
HTT P42858 1/20 0.42
NCOA1 Q15788 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
NCOA3 Q9Y6Q9 1/20 0.42
CPA1 P15085 2/20 0.42
CPA3 P15088 2/20 0.42
FOLH1 Q04609 1/20 0.42
CPB1 P15086 1/20 0.42
CPB2 Q96IY4 1/20 0.42
SRR Q9GZT4 2/20 0.41
EPHX1 P07099 1/20 0.41
SLC1A3 P43003 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3961925 0.85 CYP1A2 (0.55) CYP1A2ALPIPKMPTGS1XIAP
SCHEMBL2928010 0.85 CYP1A2 (0.55) CYP1A2ALPIPKMPTGS1XIAP
Hydrochloric Acid SCHEMBL9514047 0.83 CYP1A2 (0.53) CYP1A2ALPIPKMPTGS1XIAP
SCHEMBL27418403 0.81 CYP1A2 (0.47) CYP1A2ALPIPKMPTGS1XIAP
SCHEMBL27814583 0.81 CTRB1 (0.51) CYP1A2ALPIPKMPTGS1XIAP
SCHEMBL11088938 0.80 MDM2 (0.59) CYP1A2ALPIPKMPTGS1XIAP
SCHEMBL6845371 0.80 CYP1A2 (0.46) CYP1A2ALPIPKMPTGS1XIAP
Ethylene SCHEMBL28138727 0.80 CTRB1 (0.50) CYP1A2ALPIPKMPTGS1XIAP
Acetic Acid SCHEMBL27384315 0.80 ALPI (0.52) CYP1A2ALPIPKMPTGS1XIAP
SCHEMBL28618747 0.79 NPC1 (0.46) CYP1A2ALPIPKMPTGS1XIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0256763-B1 Process for azetidinones UNIV NOTRE DAME DU LAC (US) 1993-12-08 EP disclosed
US-4751296-A WITH POSITIVE HALOGEN IN THE PRESENCE OF WEAK BASE UNIVERSITY OF NOTRE DAME DU LAC (US) 1988-06-14 US disclosed
EP-0256763-A1 Process for azetidinones THE UNIVERSITY OF NOTRE DAME DU LAC (US) 1988-02-24 EP disclosed