Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 11/20 | 0.55 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.54 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.54 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.54 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.54 |
| ▸ | CHRNA1 | P02708 | 2/20 | 0.54 |
| ▸ | CHRNG | P07510 | 2/20 | 0.54 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.54 |
| ▸ | CHRND | Q07001 | 2/20 | 0.54 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.54 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.54 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL9785790 | 0.92 | CHRNA1 (0.52) | GRIA1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL6387020 | 0.78 | NAAA (0.76) | GRIA1CHRNA1CHRNGCHRNB1CHRND | |
| SCHEMBL6388581 | 0.78 | NAAA (0.76) | GRIA1CHRNA1CHRNGCHRNB1CHRND | |
| SCHEMBL4881390 | 0.78 | NAAA (0.76) | GRIA1CHRNA1CHRNGCHRNB1CHRND | |
| SCHEMBL7326932 | 0.77 | GRIN1 (0.60) | GRIA1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL2614261 | 0.75 | GRIN1 (0.58) | GRIA1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL12085636 | 0.74 | CNR1 (0.60) | CHRNB2CHRNB4CHRNA3CHRNA4CHRNA1 | |
| SCHEMBL398742 | 0.74 | CHRNA1 (0.64) | GRIA1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL9772212 | 0.73 | CA12 (0.52) | GRIA1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL10888477 | 0.73 | CA12 (0.52) | GRIA1CHRNB2CHRNB4CHRNA3CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0361687-B1 | Therapeutic polyamine-amides | BRITISH TECH GROUP (GB) | 1993-10-27 | — | — | EP | disclosed |