Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.32 |
| ▸ | CDK9 | P50750 | 1/20 | 0.32 |
| ▸ | GABRP | O00591 | 1/20 | 0.31 |
| ▸ | GABRD | O14764 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.31 |
| ▸ | GABRE | P78334 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11285838 | 0.75 | EGFR (0.41) | EGFRMAPTHTTTSHRCCNT1 | |
| SCHEMBL12895124 | 0.73 | PGK1 (0.45) | EGFRMAPTHTTTSHRCCNT1 | |
| SCHEMBL9448834 | 0.73 | EGFR (0.39) | EGFRMAPTHTTTSHRCCNT1 | |
| SCHEMBL17367875 | 0.73 | EGFR (0.39) | EGFRMAPTHTTTSHRHDAC1 | |
| SCHEMBL16556012 | 0.72 | CCNT1 (0.39) | EGFRMAPTHTTTSHRCCNT1 | |
| SCHEMBL28088559 | 0.70 | EPHX2 (0.46) | EGFRMAPTHTTTSHREPHX2 | |
| SCHEMBL916350 | 0.69 | CCNT1 (0.43) | EGFRMAPTHTTTSHRCCNT1 | |
| SCHEMBL28546352 | 0.69 | CA1 (0.48) | MAPTHTTTSHRCCNT1CDK9 | |
| SCHEMBL20832270 | 0.68 | GAA (0.42) | EGFRMAPTTSHRCCNT1CDK9 | |
| SCHEMBL9512164 | 0.68 | EGFR (0.34) | EGFRMAPTHTTTSHRCCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0313002-B1 | Phenyl glycines for use in reducing neurotoxic injury | SEARLE & CO (US) | 1993-12-01 | — | — | EP | disclosed |
| US-4918064-A | TREATMENT OF ANOXIA OR ISCHEMIA | G. D. SEARLE & CO. (US) | 1990-04-17 | — | — | US | disclosed |
| EP-0313002-A2 | Phenyl glycines for use in reducing neurotoxic injury | G.D. Searle & Co. (US) | 1989-04-26 | — | — | EP | disclosed |