Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MELK | Q14680 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9515742 | 0.87 | CSF1R (0.50) | — | |
| SCHEMBL9515609 | 0.86 | — | — | |
| SCHEMBL9513396 | 0.85 | — | — | |
| SCHEMBL9271579 | 0.81 | — | — | |
| SCHEMBL9265956 | 0.76 | — | — | |
| SCHEMBL9267856 | 0.76 | — | — | |
| SCHEMBL9508799 | 0.73 | — | — | |
| SCHEMBL9260685 | 0.73 | ATP4A (0.57) | — | |
| SCHEMBL9513071 | 0.72 | — | — | |
| SCHEMBL5930028 | 0.72 | CSF1R (0.63) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0330485-B1 | 4-AMINO-3-ACYL QUINOLINE DERIVATIVES AND THEIR USE AS INHIBITORS OF GASTRIC ACID SECRETION | SmithKline Beecham Intercredit B.V. (NL) | 1993-05-26 | — | — | EP | claimed |