Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.66 |
| ▸ | IDO1 | P14902 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23009194 | 0.88 | CHRM2 (0.72) | CHRM2IDO1MEN1KMT2ACYP3A4 | |
| SCHEMBL12652131 | 0.85 | CHRM2 (0.62) | CHRM2IDO1MEN1KMT2ACYP3A4 | |
| SCHEMBL6072254 | 0.84 | CHRM2 (0.72) | CHRM2IDO1MEN1KMT2ACYP3A4 | |
| Iodide SCHEMBL9478324 | 0.82 | CHRM2 (0.69) | CHRM2IDO1MEN1KMT2ACYP3A4 | |
| SCHEMBL9097242 | 0.79 | CHRM2 (0.66) | CHRM2MEN1KMT2ACYP3A4CYP2D6 | |
| SCHEMBL18939702 | 0.79 | CHRM2 (0.66) | CHRM2MEN1KMT2ACYP3A4CYP2D6 | |
| SCHEMBL4706607 | 0.79 | CHRM2 (0.71) | CHRM2IDO1MEN1KMT2ACYP3A4 | |
| SCHEMBL5767474 | 0.79 | TAAR1 (0.61) | CHRM2MEN1KMT2ACYP3A4CYP2D6 | |
| SCHEMBL6869146 | 0.78 | IDO1 (0.58) | CHRM2IDO1MEN1KMT2ACYP3A4 | |
| SCHEMBL8427041 | 0.78 | CA12 (0.77) | CYP2D6CA12CA2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0320910-B1 | 2-Thiazolidinone derivatives, pharmaceutical compositions containing them, process for preparing same, and use | RICHTER GEDEON VEGYESZET (HU) | 1993-12-08 | — | — | EP | disclosed |
| CN-1019196-B | Process for preparing 2-thiazolidinone derivatives | RICHTER GEDEON VEGYESZET (HU) | 1992-11-25 | — | — | CN | disclosed |
| US-4937252-A | 2-thiazolidinone derivatives, pharmaceutical compositions containing them and process for preparing same | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1990-06-26 | — | — | US | disclosed |
| CN-1033625-A | 2-thiazolidinone derivatives, pharmaceutical compositions containing the same, and process for producing the same | RICHTER GEDEON VEGYESZET (HU) | 1989-07-05 | — | — | CN | disclosed |
| EP-0320910-A1 | 2-Thiazolidinone derivatives, pharmaceutical compositions containing them, process for preparing same, and use | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1989-06-21 | — | — | EP | disclosed |