Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.57 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | IDH1 | O75874 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9515008 | 1.00 | TRPV1 (0.57) | TRPV1EPHX2LMNAGAASSTR4 | |
| SCHEMBL9513695 | 1.00 | TRPV1 (0.57) | TRPV1EPHX2LMNAGAASSTR4 | |
| SCHEMBL24575927 | 0.86 | EPHX2 (0.64) | TRPV1EPHX2LMNAGAASSTR4 | |
| SCHEMBL14004671 | 0.82 | EPHX2 (0.60) | TRPV1EPHX2LMNAGAASSTR4 | |
| SCHEMBL16480210 | 0.82 | EPHX2 (0.60) | TRPV1EPHX2LMNAGAASSTR4 | |
| SCHEMBL14025088 | 0.82 | EPHX2 (0.60) | TRPV1EPHX2LMNAGAASSTR4 | |
| SCHEMBL16477697 | 0.81 | EPHX2 (0.56) | TRPV1EPHX2LMNAGAASSTR4 | |
| SCHEMBL2692933 | 0.81 | EPHX2 (0.59) | TRPV1EPHX2LMNAGAASSTR4 | |
| SCHEMBL9680229 | 0.80 | SMN1; SMN2 (0.54) | EPHX2LMNAGAAKMT2AMEN1 | |
| SCHEMBL31616384 | 0.80 | IDH1 (0.54) | TRPV1EPHX2LMNAGAASSTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0344425-B1 | N-[[(2,6-disubstituted)phenyl]-N'- arylalkyl] ureas as antihypercholesterolemic and antiatherosclerotic agents | WARNER LAMBERT CO (US) | 1993-12-08 | — | — | EP | claimed |