Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | SOAT2 | O75908 | 2/20 | 0.48 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CASR | P41180 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9678718 | 0.85 | KMT2A (0.55) | SMN1; SMN2KMT2AMEN1KDM4ESOAT2 | |
| SCHEMBL9678591 | 0.82 | KMT2A (0.63) | SMN1; SMN2KMT2AMEN1KDM4ESOAT2 | |
| SCHEMBL9678933 | 0.82 | KMT2A (0.63) | SMN1; SMN2KMT2AMEN1KDM4ESOAT2 | |
| SCHEMBL9678585 | 0.82 | KMT2A (0.63) | SMN1; SMN2KMT2AMEN1KDM4ESOAT2 | |
| SCHEMBL9680727 | 0.82 | SMN1; SMN2 (0.60) | SMN1; SMN2KMT2AMEN1KDM4ESOAT2 | |
| SCHEMBL20377967 | 0.80 | EPHX2 (0.52) | LMNAGAACASREPHX2 | |
| SCHEMBL16034079 | 0.80 | EPHX2 (0.52) | LMNAGAACASREPHX2 | |
| SCHEMBL20377971 | 0.80 | EPHX2 (0.52) | LMNAGAACASREPHX2 | |
| SCHEMBL9514720 | 0.80 | TRPV1 (0.57) | KMT2AMEN1LMNAGAAEPHX2 | |
| SCHEMBL9513695 | 0.80 | TRPV1 (0.57) | KMT2AMEN1LMNAGAAEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415413-A1 | Acat inhibitors | WARNER-LAMBERT COMPANY (US) | 1991-03-06 | — | — | EP | claimed |
| US-5153226-A | Administering as anticholesterol agents, for atherosclerosis | WARNER-LAMBERT COMPANY (US) | 1992-10-06 | — | — | US | disclosed |
| EP-0415413-A1 | Acat inhibitors | WARNER-LAMBERT COMPANY (US) | 1991-03-06 | — | — | EP | disclosed |