Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.71 |
| ▸ | HPGD | P15428 | 3/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.71 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | GALR3 | O60755 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2277189 | 0.88 | L3MBTL1 (0.58) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL5426590 | 0.86 | L3MBTL1 (1.00) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL28135680 | 0.84 | KDM4E (0.60) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL4369004 | 0.83 | KDM4E (1.00) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL10085396 | 0.83 | KDM4E (0.77) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9410563 | 0.82 | SMN1; SMN2 (0.67) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL4502502 | 0.82 | KDM4E (0.75) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL8687313 | 0.81 | L3MBTL1 (0.65) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL12883756 | 0.79 | KDM4E (0.71) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL2730305 | 0.79 | KDM4E (0.71) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0382533-B1 | INDOLE DERIVATES | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (ES) | 1993-01-27 | — | — | EP | disclosed |
| US-5130327-A | Antidepressants | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (ES) | 1992-07-14 | — | — | US | disclosed |
| WO-1990009375-A1 | INDOLE DERIVATIVES | CONSEJO SUPERIOR INVESTIGACIONES CIENTIFICAS (ES) | 1990-08-23 | — | — | WO | disclosed |
| EP-0382533-A1 | Indole derivates | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (ES) | 1990-08-16 | — | — | EP | disclosed |