Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7372261 | 1.00 | TSHR (0.37) | TSHR | |
| SCHEMBL15847388 | 1.00 | TSHR (0.37) | TSHR | |
| SCHEMBL15370173 | 0.84 | TSHR (0.35) | TSHR | |
| SCHEMBL3288415 | 0.81 | LMNA (0.37) | TSHR | |
| SCHEMBL15847142 | 0.75 | TSHR (0.36) | TSHR | |
| SCHEMBL9514368 | 0.75 | TSHR (0.36) | TSHR | |
| SCHEMBL7373706 | 0.75 | TSHR (0.36) | TSHR | |
| SCHEMBL1609961 | 0.74 | TSHR (0.33) | TSHR | |
| SCHEMBL8271856 | 0.74 | TSHR (0.33) | TSHR | |
| SCHEMBL7114195 | 0.74 | TSHR (0.33) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0379288-B1 | Process and intermediates for isopropyl 3S-amino-2R-hydroxyalkanoates | PFIZER (US) | 1993-12-22 | — | — | EP | claimed |
| EP-0379288-A1 | Process and intermediates for isopropyl 3S-amino-2R-hydroxyalkanoates | PFIZER INC. (US) | 1990-07-25 | — | — | EP | claimed |
| US-5166400-A | Intermediates for isopropyl 3S-amino-2R-hydroxy-alkanoates | PFIZER INC. (US) | 1992-11-24 | — | — | US | disclosed |
| US-5036155-A | Process for isopropyl 3S-amino-2R-hydroxy-alkanoates | PFIZER INC. (US) | 1991-07-30 | — | — | US | disclosed |
| US-4965372-A | Process and intermediates for isopropyl 3S-amino-2R-hydroxy-alkanoates | PFIZER INC. (US) | 1990-10-23 | — | — | US | disclosed |
| EP-0379288-A1 | Process and intermediates for isopropyl 3S-amino-2R-hydroxyalkanoates | PFIZER INC. (US) | 1990-07-25 | — | — | EP | disclosed |