SCHEMBL9514859

SCHEMBL9514859

O=C(O)C1OCCOCCOCCOCCOCCOC1C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SUCNR1 Q9BXA5 1/20 0.43
HSD17B10 Q99714 1/20 0.34
TTR P02766 1/20 0.33
TSHR P16473 1/20 0.32
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31196527 1.00 SUCNR1 (0.43) SUCNR1HSD17B10TTRTSHRKDM4E
SCHEMBL350769 1.00 SUCNR1 (0.43) SUCNR1HSD17B10TTRTSHRKDM4E
SCHEMBL9516478 1.00 SUCNR1 (0.43) SUCNR1HSD17B10TTRTSHRKDM4E
SCHEMBL28611363 0.91 SUCNR1 (0.50) SUCNR1TSHRKDM4EALDH1A1
SCHEMBL9514945 0.83 THRB (0.39) SUCNR1TSHR
SCHEMBL6793013 0.82 SUCNR1 (0.30) SUCNR1
SCHEMBL11298204 0.78 SUCNR1 (0.43) SUCNR1KDM4EALDH1A1
SCHEMBL6789695 0.76 KDM4E (0.37) TTRKDM4ESMN1; SMN2
SCHEMBL7683264 0.74 SUCNR1 (0.39) SUCNR1KDM4EALDH1A1
SCHEMBL731703 0.73 SUCNR1 (0.50) SUCNR1TSHRKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0341409-B1 Platinum (II) complexes, their preparation and use as antitumour agents BOEHRINGER MANNHEIM ITALIA (IT) 1993-12-29 EP disclosed
EP-0415939-A1 PLATINUM(II) COMPLEXES, THEIR PREPARATION AND USE AS ANTI-TUMOUR AGENTS BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) 1991-03-13 EP disclosed
EP-0341409-A1 Platinum (II) complexes, their preparation and use as antitumour agents BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) 1989-11-15 EP disclosed
WO-1989009218-A1 PLATINUM(II) COMPLEXES, THEIR PREPARATION AND USE AS ANTI-TUMOUR AGENTS BOEHRINGER BIOCHEMIA ROBIN S.P.A. (IT) 1989-10-05 WO disclosed