Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12944196 | 0.93 | HSP90AA1 (0.87) | HSP90AA1 | |
| SCHEMBL2694025 | 0.89 | HSP90AA1 (1.00) | HSP90AA1 | |
| SCHEMBL2694024 | 0.89 | HSP90AA1 (1.00) | HSP90AA1 | |
| SCHEMBL420309 | 0.87 | HSP90AA1 (1.00) | HSP90AA1 | |
| SCHEMBL13190306 | 0.87 | HSP90AA1 (1.00) | HSP90AA1 | |
| SCHEMBL420310 | 0.87 | HSP90AA1 (1.00) | HSP90AA1 | |
| SCHEMBL953524 | 0.87 | HSP90AA1 (0.76) | HSP90AA1 | |
| SCHEMBL949997 | 0.86 | HSP90AA1 (0.75) | HSP90AA1 | |
| SCHEMBL949494 | 0.85 | HSP90AA1 (1.00) | HSP90AA1 | |
| SCHEMBL2695206 | 0.85 | HSP90AA1 (0.94) | HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011004132-A1 | NOVEL HSP90-INHIBITING INDOLE DERIVATIVES, COMPOSITIONS CONTAINING SAID DERIVATIVES, AND USE THEREOF | SANOFI-AVENTIS (FR) | 2011-01-13 | — | — | WO | claimed |
| WO-2011004132-A1 | NOVEL HSP90-INHIBITING INDOLE DERIVATIVES, COMPOSITIONS CONTAINING SAID DERIVATIVES, AND USE THEREOF | SANOFI-AVENTIS (FR) | 2011-01-13 | — | — | WO | disclosed |