Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.33 |
| ▸ | MMP2 | P08253 | 2/20 | 0.30 |
| ▸ | MMP9 | P14780 | 2/20 | 0.30 |
| ▸ | CA12 | O43570 | 2/20 | 0.30 |
| ▸ | CA1 | P00915 | 2/20 | 0.30 |
| ▸ | CA2 | P00918 | 2/20 | 0.30 |
| ▸ | CA9 | Q16790 | 2/20 | 0.30 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP3 | P08254 | 1/20 | 0.30 |
| ▸ | MMP8 | P22894 | 1/20 | 0.30 |
| ▸ | MMP13 | P45452 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9517544 | 1.00 | EPHX2 (0.33) | EPHX2MMP2MMP9CA12CA1 | |
| SCHEMBL9517505 | 1.00 | EPHX2 (0.33) | EPHX2MMP2MMP9CA12CA1 | |
| SCHEMBL9516450 | 1.00 | EPHX2 (0.33) | EPHX2MMP2MMP9CA12CA1 | |
| SCHEMBL9514924 | 1.00 | EPHX2 (0.33) | EPHX2MMP2MMP9CA12CA1 | |
| SCHEMBL9517602 | 1.00 | EPHX2 (0.33) | EPHX2MMP2MMP9CA12CA1 | |
| SCHEMBL9516482 | 0.85 | MME (0.32) | EPHX2 | |
| SCHEMBL9516411 | 0.85 | MME (0.32) | EPHX2 | |
| Ethylenediamine SCHEMBL9515470 | 0.84 | CA2 (0.33) | CA2 | |
| SCHEMBL9516608 | 0.82 | CA2 (0.32) | CA2 | |
| SCHEMBL9800619 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0341409-B1 | Platinum (II) complexes, their preparation and use as antitumour agents | BOEHRINGER MANNHEIM ITALIA (IT) | 1993-12-29 | — | — | EP | claimed |
| US-5104895-A | PLATINUM(II) COMPLEXES, THEIR PREPARATION AND USE AS ANTI-TUMOR AGENTS | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1992-04-14 | — | — | US | claimed |
| EP-0415939-A1 | PLATINUM(II) COMPLEXES, THEIR PREPARATION AND USE AS ANTI-TUMOUR AGENTS | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1991-03-13 | — | — | EP | claimed |
| WO-1989009218-A1 | PLATINUM(II) COMPLEXES, THEIR PREPARATION AND USE AS ANTI-TUMOUR AGENTS | BOEHRINGER BIOCHEMIA ROBIN S.P.A. (IT) | 1989-10-05 | — | — | WO | claimed |
| EP-0341409-B1 | Platinum (II) complexes, their preparation and use as antitumour agents | BOEHRINGER MANNHEIM ITALIA (IT) | 1993-12-29 | — | — | EP | disclosed |