Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | P4HB | P07237 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.39 |
| ▸ | CLK1 | P49759 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9514917 | 1.00 | MAPT (0.42) | MAPTKMT2ARAB9AMEN1KDM4E | |
| SCHEMBL9514542 | 0.83 | MEN1 (0.56) | MAPTKMT2ARAB9AMEN1ALDH1A1 | |
| SCHEMBL9514551 | 0.83 | MEN1 (0.56) | MAPTKMT2ARAB9AMEN1ALDH1A1 | |
| SCHEMBL9337056 | 0.83 | KAT8 (0.48) | MAPTKMT2ARAB9AMEN1KDM4E | |
| SCHEMBL9334957 | 0.83 | KAT8 (0.48) | MAPTKMT2ARAB9AMEN1KDM4E | |
| SCHEMBL9337075 | 0.83 | KAT8 (0.48) | MAPTKMT2ARAB9AMEN1KDM4E | |
| SCHEMBL9389070 | 0.83 | KAT8 (0.48) | MAPTKMT2ARAB9AMEN1KDM4E | |
| SCHEMBL7898872 | 0.77 | PTPN1 (0.61) | MAPTKMT2ARAB9AMEN1KDM4E | |
| SCHEMBL9335180 | 0.77 | KAT8 (0.50) | MAPTKMT2ARAB9AMEN1KDM4E | |
| SCHEMBL9335185 | 0.77 | KAT8 (0.50) | MAPTKMT2ARAB9AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0219436-B1 | Thiazole derivative and leukotriene antagonist containing the same as the effective ingredients | MITSUBISHI CHEM IND (JP) | 1993-12-22 | — | — | EP | disclosed |
| US-4902700-A | Thiazole derivative and leukotriene antagonist containing the same as the effective ingredients | MITSUBISHI KASEI CORPORATION (JP) | 1990-02-20 | — | — | US | disclosed |
| EP-0219436-A2 | Thiazole derivative and leukotriene antagonist containing the same as the effective ingredients | MITSUBISHI KASEI CORPORATION (JP) | 1987-04-22 | — | — | EP | disclosed |