Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.48 |
| ▸ | ATP4A | P20648 | 1/20 | 0.46 |
| ▸ | ATP4B | P51164 | 1/20 | 0.46 |
| ▸ | P4HB | P07237 | 3/20 | 0.44 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.43 |
| ▸ | PFKFB4 | Q16877 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9337056 | 1.00 | KAT8 (0.48) | KAT8ATP4AATP4BP4HBPFKFB3 | |
| SCHEMBL9389070 | 0.87 | KAT8 (0.48) | KAT8P4HBMAPTRAB9AKDM4E | |
| SCHEMBL9334957 | 0.87 | KAT8 (0.48) | KAT8P4HBMAPTRAB9AKDM4E | |
| SCHEMBL9514915 | 0.83 | MAPT (0.42) | P4HBMAPTRAB9AKDM4EMEN1 | |
| SCHEMBL9514917 | 0.83 | MAPT (0.42) | P4HBMAPTRAB9AKDM4EMEN1 | |
| SCHEMBL9514542 | 0.79 | MEN1 (0.56) | MAPTRAB9ACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL9514551 | 0.79 | MEN1 (0.56) | MAPTRAB9ACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL4957634 | 0.79 | CYSLTR1 (0.60) | MAPTL3MBTL1KDM4EMEN1ALDH1A1 | |
| SCHEMBL24410997 | 0.77 | P4HB (0.57) | P4HBMAPTRAB9ACYP3A4CYP2C9 | |
| SCHEMBL22887387 | 0.77 | P4HB (0.57) | P4HBMAPTRAB9ACYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533695-B1 | IMIDAZO (4,5-c) PYRIDINES WITH PAF ANTAGONIST ACTIVITY | PFIZER (US) | 1994-10-05 | — | — | EP | disclosed |
| US-5322847-A | Inhibit platelet activating factor, block leukotriene D4 receptors | PFIZER INC. (US) | 1994-06-21 | — | — | US | disclosed |
| EP-0533695-A1 | IMIDAZO (4,5-c) PYRIDINES WITH PAF ANTAGONIST ACTIVITY. | PFIZER (US) | 1993-03-31 | — | — | EP | disclosed |
| WO-1991017163-A1 | IMIDAZO (4,5-c) PYRIDINES WITH PAF ANTAGONIST ACTIVITY | PFIZER INC. (US) | 1991-11-14 | — | — | WO | disclosed |