Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 1/20 | 0.53 |
| ▸ | ACE | P12821 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KLK7 | P49862 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9518695 | 0.83 | MME (0.73) | MMEACEMEN1KMT2ALMNA | |
| SCHEMBL19965677 | 0.83 | CA1 (0.62) | MEN1KMT2ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL20852746 | 0.83 | CA1 (0.62) | MEN1KMT2ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL26503489 | 0.81 | MEN1 (0.51) | MEN1KMT2ALMNAALDH1A1TSHR | |
| SCHEMBL5227347 | 0.78 | ALDH1A1 (0.61) | MEN1KMT2ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL28581175 | 0.77 | MEN1 (0.57) | MEN1KMT2ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL7086042 | 0.77 | MEN1 (0.57) | MEN1KMT2ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL28589171 | 0.77 | MEN1 (0.57) | MEN1KMT2ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL11744810 | 0.77 | MEN1 (0.60) | MEN1KMT2ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL2610082 | 0.76 | MEN1 (0.74) | MEN1KMT2ASMN1; SMN2TSHRKLK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0410726-B1 | S-SUBSTITUTED BETA-THIOACRYLAMIDES AND THEIR USE AS MICROBICIDES | ROHM AND HAAS COMPANY (US) | 1993-09-01 | — | — | EP | disclosed |
| US-5151447-A | Bactericides and fungicides | ROHM AND HAAS COMPANY (US) | 1992-09-29 | — | — | US | disclosed |
| US-5023275-A | S-substituted beta-thioacrylamide biocides and fungicides | ROHM AND HAAS COMPANY (US) | 1991-06-11 | — | — | US | disclosed |
| EP-0410726-A1 | S-substituted beta-thioacrylamides and their use as microbicides | ROHM AND HAAS COMPANY (US) | 1991-01-30 | — | — | EP | disclosed |