Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 10/20 | 0.59 |
| ▸ | TTR | P02766 | 1/20 | 0.56 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.55 |
| ▸ | TYR | P14679 | 1/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.50 |
| ▸ | STAT3 | P40763 | 2/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.50 |
| ▸ | RELA | Q04206 | 2/20 | 0.50 |
| ▸ | MMP9 | P14780 | 2/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.50 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.50 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.50 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.50 |
| ▸ | CAMK2A | Q9UQM7 | 2/20 | 0.50 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | KDR | P35968 | 1/20 | 0.50 |
| ▸ | XDH | P47989 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29904497 | 0.89 | TUBB1 (0.57) | APPALOX5MAPTCYP1A2MEN1 | |
| SCHEMBL151091 | 0.87 | MAPT (0.53) | APPTTRNFE2L2PTGS2MAPT | |
| SCHEMBL21940413 | 0.87 | MAPT (0.53) | APPTTRNFE2L2PTGS2MAPT | |
| SCHEMBL29417481 | 0.87 | MAPT (0.53) | APPTTRNFE2L2PTGS2MAPT | |
| SCHEMBL151090 | 0.87 | MAPT (0.53) | APPTTRNFE2L2PTGS2MAPT | |
| SCHEMBL29363338 | 0.87 | MAPT (0.53) | APPTTRNFE2L2PTGS2MAPT | |
| SCHEMBL1507965 | 0.82 | TUBB1 (0.42) | APPNFE2L2PTGS2MAPTCYP1A2 | |
| SCHEMBL14407712 | 0.82 | TUBB1 (0.42) | APPNFE2L2PTGS2MAPTCYP1A2 | |
| SCHEMBL19750562 | 0.82 | ALDH1A1 (0.43) | APPNFE2L2MAPTCYP1A2MEN1 | |
| SCHEMBL147173 | 0.81 | CYP1A1 (0.51) | MAPTCYP1A2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0303945-B1 | Photosensitive composition based on 1,2-naphthoquinone diazides, and copying material prepared therefrom | HOECHST AG (DE) | 1993-11-24 | — | — | EP | disclosed |
| EP-0234570-B1 | PHOTOPOLYMERIZABLE COMPOSITION, PHOTOSENSITIVE ELEMENT WITH THAT COMPOSITION, AND PROCESS FOR THE PRODUCTION OF A LITHOGRAPHIC PRINTING PLATE USING THIS ELEMENT | BASF Aktiengesellschaft (DE) | 1992-04-22 | — | — | EP | disclosed |
| US-4935330-A | Photopolymerizable mixture, photosensitive recording element containing this mixture, and the production of lithographic printing plate using this photosensitive recording element | BASF AKTIENGESELLSCHAFT (DE) | 1990-06-19 | — | — | US | disclosed |
| EP-0303945-A2 | Photosensitive composition based on 1,2-naphthoquinone diazides, and copying material prepared therefrom | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-02-22 | — | — | EP | disclosed |
| US-4758497-A | Photosensitive naphthoquinone diazide sulfonyl ester compounds for the fabrication of lithographic plates and photosensitive sheet construction with the compounds | POLYCHROME CORPORATION (US) | 1988-07-19 | — | — | US | disclosed |