Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GDA | Q9Y2T3 | 2/20 | 0.41 |
| ▸ | PNP | P00491 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | BLM | P54132 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28383481 | 0.78 | PNP (0.38) | GDAPNPALDH1A1KDM4EBLM | |
| SCHEMBL4560085 | 0.77 | GDA (0.53) | GDAPNPALDH1A1MEN1KMT2A | |
| SCHEMBL10998 | 0.77 | GDA (0.53) | GDAPNPALDH1A1MEN1KMT2A | |
| SCHEMBL2562945 | 0.76 | PNP (0.38) | GDAPNPALDH1A1KDM4EBLM | |
| SCHEMBL9669020 | 0.76 | PNP (0.35) | GDAPNPALDH1A1KDM4EBLM | |
| SCHEMBL2352519 | 0.76 | PNP (0.43) | GDAPNPALDH1A1MEN1KMT2A | |
| Ammonia Solution, Strong SCHEMBL28309009 | 0.75 | GDA (0.51) | GDAPNPALDH1A1MEN1KMT2A | |
| SCHEMBL28079039 | 0.75 | GDA (0.51) | GDAPNPALDH1A1MEN1KMT2A | |
| SCHEMBL27708662 | 0.75 | GDA (0.51) | GDAPNPALDH1A1MEN1KMT2A | |
| SCHEMBL21539483 | 0.73 | GDA (0.36) | GDAPNPALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5156033-A | — | — | None | — | — | JP | disclosed |
| EP-3013340-B9 | SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF | JANSSEN PHARMACEUTICALS INC (US) | 2023-10-04 | — | — | EP | disclosed |
| EP-3013340-B1 | SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF | JANSSEN BIOPHARMA INC (US) | 2023-06-07 | — | — | EP | disclosed |
| EP-3797782-A1 | SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF FOR USE IN THE TREATMENT OF VIRAL INFECTIONS | Janssen BioPharma, Inc. (US) | 2021-03-31 | — | — | EP | disclosed |
| EP-2616513-B1 | CATALYSTS AND METHODS FOR POLYMER SYNTHESIS | SAUDI ARAMCO TECH CO (SA) | 2019-11-06 | — | — | EP | disclosed |
| EP-3466959-A1 | SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF | Janssen BioPharma, Inc. (US) | 2019-04-10 | — | — | EP | disclosed |
| EP-3424938-A1 | 4'-AZIDOALKYL-SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF | Alios Biopharma, Inc. (US) | 2019-01-09 | — | — | EP | disclosed |
| WO-2018144955-A1 | CONSTRUCT-PEPTIDE COMPOSITIONS AND METHODS OF USE THEREOF | SILVERBACK THERAPEUTICS, INC. (US) | 2018-08-09 | — | — | WO | disclosed |
| EP-3013843-B1 | SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF | ALIOS BIOPHARMA INC (US) | 2018-05-30 | — | — | EP | disclosed |
| JP-H05156033-A | PR0DUCTION OF CROSSLINKED POLYOLEFIN MOLDING | MITSUI TOATSU CHEM INC | 1993-06-22 | — | — | JP | disclosed |