Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.33 |
| ▸ | TYMP | P19971 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9515053 | 0.76 | GDA (0.41) | PNPMAPTGDAALDH1A1KDM4E | |
| SCHEMBL21682417 | 0.76 | KMT2A (0.37) | PNPMAPTKDM4CGDATYMP | |
| SCHEMBL2562945 | 0.71 | PNP (0.38) | PNPGDAALDH1A1KDM4ECYP1A2 | |
| SCHEMBL2352519 | 0.70 | PNP (0.43) | PNPMAPTGDAALDH1A1KDM4E | |
| SCHEMBL27543832 | 0.69 | HCAR1 (0.54) | ALDH1A1KDM4EADORA2ARAB9AHSD17B10 | |
| SCHEMBL6275156 | 0.68 | PNP (0.42) | PNPMAPTGDAALDH1A1KDM4E | |
| SCHEMBL618978 | 0.67 | PNP (0.44) | PNPMAPTGDAALDH1A1KDM4E | |
| SCHEMBL133948 | 0.67 | PNP (0.41) | PNPMAPTGDAALDH1A1KDM4E | |
| SCHEMBL4560085 | 0.67 | GDA (0.53) | PNPMAPTGDAALDH1A1KDM4E | |
| SCHEMBL13007561 | 0.67 | PNP (0.41) | PNPMAPTGDAALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0505543-A1 | NOVEL p-SUBSTITUTED PHENYL 4-OXYBUTANE AMINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LABORATOIRE THERAMEX (MC) | 1992-09-30 | — | — | EP | claimed |
| WO-1992006977-A1 | NOVEL p-SUBSTITUTED PHENYL 4-OXYBUTANE AMINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LABORATOIRE THERAMEX S.A. (MC) | 1992-04-30 | — | — | WO | claimed |
| EP-0505543-A1 | NOVEL p-SUBSTITUTED PHENYL 4-OXYBUTANE AMINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LABORATOIRE THERAMEX (MC) | 1992-09-30 | — | — | EP | disclosed |
| WO-1992006977-A1 | NOVEL p-SUBSTITUTED PHENYL 4-OXYBUTANE AMINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LABORATOIRE THERAMEX S.A. (MC) | 1992-04-30 | — | — | WO | disclosed |