Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.67 |
| ▸ | DRD3 | P35462 | 3/20 | 0.67 |
| ▸ | GRIN2B | Q13224 | 6/20 | 0.66 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.56 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.54 |
| ▸ | ACHE | P22303 | 2/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.53 |
| ▸ | FYN | P06241 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9516292 | 1.00 | DRD2 (0.67) | DRD2DRD3GRIN2BGRIN1KMT2A | |
| SCHEMBL355042 | 1.00 | DRD2 (0.67) | DRD2DRD3GRIN2BGRIN1KMT2A | |
| Hydrochloric Acid SCHEMBL8767433 | 0.99 | DRD2 (0.65) | DRD2DRD3GRIN2BGRIN1KMT2A | |
| Hydrochloric Acid SCHEMBL9304463 | 0.99 | DRD2 (0.65) | DRD2DRD3GRIN2BGRIN1KMT2A | |
| Hydrochloric Acid SCHEMBL9305508 | 0.99 | DRD2 (0.65) | DRD2DRD3GRIN2BGRIN1KMT2A | |
| SCHEMBL12524812 | 0.95 | GRIN2B (0.66) | DRD2DRD3GRIN2BGRIN1KMT2A | |
| SCHEMBL8765599 | 0.93 | DRD2 (0.57) | DRD2DRD3GRIN2BGRIN1KMT2A | |
| SCHEMBL5143730 | 0.93 | DRD2 (0.57) | DRD2DRD3GRIN2BGRIN1KMT2A | |
| Hydrochloric Acid SCHEMBL8765371 | 0.91 | DRD2 (0.56) | DRD2DRD3GRIN2BGRIN1KMT2A | |
| Hydrochloric Acid SCHEMBL8765358 | 0.91 | DRD2 (0.56) | DRD2DRD3GRIN2BGRIN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0347313-B1 | 2-Amino-7-hydroxytetraline ethers | SANOFI ELF (FR) | 1993-12-15 | — | — | EP | disclosed |
| EP-0383686-B1 | 2-AMINO-7-HYDROXYTETRALINE CARBOXYALKYL ETHERS | ELF SANOFI (FR) | 1993-08-04 | — | — | EP | disclosed |
| EP-0383686-A1 | 2-Amino-7-hydroxytetraline carboxyalkyl ethers | ELF SANOFI (FR) | 1990-08-22 | — | — | EP | disclosed |
| EP-0347313-A2 | 2-Amino-7-hydroxytetraline ethers | ELF SANOFI (FR) | 1989-12-20 | — | — | EP | disclosed |