SCHEMBL9515262

SCHEMBL9515262

CCOP(=O)(Cc1ccc(P(=O)(OCC)OCC)cc1)OCC

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.42
NPY5R Q15761 1/20 0.41
TDP1 Q9NUW8 1/20 0.40
TSHR P16473 1/20 0.40
LTA4H P09960 1/20 0.39
EPHX2 P34913 1/20 0.39
CCNT1 O60563 2/20 0.38
CDK9 P50750 2/20 0.38
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA4 P22748 1/20 0.37
CA5A P35218 1/20 0.37
CA7 P43166 1/20 0.37
CA9 Q16790 1/20 0.37
CA5B Q9Y2D0 1/20 0.37
TLR8 Q9NR97 1/20 0.36
TLR7 Q9NYK1 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3375825 0.88 TSHR (0.50) POLBNPY5RTDP1TSHRCCNT1
SCHEMBL11250226 0.86 POLB (0.39) POLBNPY5RTDP1TSHRLTA4H
SCHEMBL6829825 0.84 TDP1 (0.49) POLBTDP1TSHRLTA4HEPHX2
SCHEMBL11140840 0.82 POLB (0.54) POLBTDP1TSHRLTA4HEPHX2
SCHEMBL2493713 0.82 TSHR (0.44) POLBNPY5RTSHRCCNT1CDK9
SCHEMBL16062693 0.82 POLB (0.46) POLBNPY5RTDP1TSHRCCNT1
SCHEMBL23822678 0.81 TSHR (0.43) POLBNPY5RTSHRCCNT1CDK9
SCHEMBL915242 0.81 TSHR (0.43) POLBNPY5RTSHRCCNT1CDK9
SCHEMBL25923558 0.81 TSHR (0.43) POLBNPY5RTSHRCCNT1CDK9
SCHEMBL13981576 0.79 NPY5R (0.42) POLBNPY5RTSHRCCNT1CDK9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7459106-B2 Materials, methods, and uses for photochemical generation of acids and/or radical species THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2008-12-02 US disclosed
EP-0303186-B1 Aryl phosphorus derivatives, their preparation and their use BASF AG (DE) 1993-11-10 EP disclosed
US-4918212-A Arylphosphorus derivatives BASF AKTIENGESELLSCHAFT (DE) 1990-04-17 US disclosed
EP-0303186-A2 Aryl phosphorus derivatives, their preparation and their use BASF Aktiengesellschaft (DE) 1989-02-15 EP disclosed
US-4317782-A DYE LASERS, WHITENERS BAYER AKTIENGESELLSCHAFT (DE) 1982-03-02 US disclosed